TWiM #2: The plague, microbial virulence and the gut microbiome

TWiM #2: The plague, microbial virulence and the gut microbiome

Author: Vincent Racaniello March 9, 2011 Duration: 1:15:43

Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity.


Dive into the fascinating world of bacteria, viruses, and fungi with This Week in Microbiology. Hosted by Vincent Racaniello, a professor of microbiology & immunology, this regular audio journey explores the latest research, news, and stories from the vast universe of microbes. Each episode feels like sitting in on a lively discussion among experts and colleagues, where complex topics are broken down with clarity and enthusiasm. The conversations are informal and engaging, designed to be understood by anyone with curiosity, whether you're a professional researcher, a student, or simply someone intrigued by the invisible forces that shape our health and planet. Building on the accessible style of Racaniello's other popular science shows, this podcast demystifies the latest scientific papers, emerging infectious diseases, and the everyday roles of microorganisms in a way that is both substantive and surprisingly entertaining. You'll hear genuine dialogue, questions from listeners, and diverse perspectives that make the science feel immediate and relevant. Tune in to discover how the smallest forms of life have some of the biggest stories to tell, all through a podcast that treats microbiology not as a distant textbook subject, but as a dynamic and ever-evolving narrative happening right now, all around us.
Author: Language: English Episodes: 354

This Week in Microbiology
Podcast Episodes
303: Can Our Microbiome Break Our Hearts? [not-audio_url] [/not-audio_url]

Duration: 56:32
TWiM reveals a database of genome sequences of thousands of Mycobaterium tuberculosis, allowing association with resistance phenotypes to 13 antibiotics, and microbe-derived uremic solutes that enhance thrombosis potenti…
302: Itching and Scratching and New Antibiotics [not-audio_url] [/not-audio_url]

Duration: 54:33
TWiM describes the mechanism for the S. aureus itch and scratch induced skin damage, and discovery of a novel class of antibiotics that targets the lipopolysaccharide transporter. Become a patron of TWiM. Links: S. aureu…
301: Another Year is Microbial [not-audio_url] [/not-audio_url]

Duration: 47:18
A highly reduced TWiM team presents a study of the use of phage diversity in cell-free DNA to identify bacterial pathogens in human sepsis cases, and the evolution, persistence, and host adaptation of a gonococcal antimi…
300: Marvels of Microbiology [not-audio_url] [/not-audio_url]

Duration: 39:30
On the occasion of TWiM's 300th episode, we discuss how two college students found a new antibiotic in soil, Barbara Iglewski's passing, and Elio returns for an appearance. Hosts: Vincent Racaniello, Michael Schmidt, Pet…
299: Teaching with TWiM [not-audio_url] [/not-audio_url]

Duration: 51:24
From ASM's Conference for Undergraduate Educators 2023 in Phoenix, TWiM speaks with Amaya Garcia Costas and Gwendolyn Knapp about their approaches to undergraduate microbiology education, and how they use TWiM as part of…
298: Impact of Lung Microbiome and Racial Disparities on Asthma [not-audio_url] [/not-audio_url]

Duration: 59:47
TWiM provides thoughts on providing better training for a non-academic career, and help celebrate Black in Microbiology Week with a 2023 paper by Ari Kozik, a co-founder of Black Microbiologists Association and Assistant…
297: Bacterial-electronic Sensor Pill [not-audio_url] [/not-audio_url]

Duration: 59:27
TWiM reviews how a coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores, and a miniaturized device that integrates genetically engineered probiotic biosensors with…
296: Bacterial Channels in Plant Cells [not-audio_url] [/not-audio_url]

Duration: 47:02
TWiM discusses a dispute about whether the mycobiome plays a role in the development of cancer, and the structure and function of channels that are delivered to plant cells by pathogenic bacteria. Hosts: Vincent Racaniel…
295: Uncultured and Unmutable [not-audio_url] [/not-audio_url]

Duration: 1:06:48
TWiM explains how phages avoid tRNA-targeting host defenses, and discovery of a new antibiotic from an uncultured bacterium that binds to an immutable target. Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin,…
294: You'll Scream After Ice Cream [not-audio_url] [/not-audio_url]

Duration: 52:37
TWiM reveals that the ice cream manufacturing environment harbors psychrotrophic bacteria, and identification of a deadly bacterial strain causing widespread deaths of newborns in Uganda. Hosts: Vincent Racaniello, Micha…