Naval's GP, Ankur Nagpal, Breaks Down The Viral “USVC” Fund | E2284

Naval's GP, Ankur Nagpal, Breaks Down The Viral “USVC” Fund | E2284

Author: Jason Calacanis May 5, 2026 Duration: 1:38:10

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Have you wanted to invest in venture capital alongside your 401k contributions, but struggled to find a way to place a bet? Search no more, for the AngelList team has created USVC, a new fund that will accept investments of as little as $500 from folks who lack accreditation. USVC’s Ankur Napgal swung by the show to chat about investment strategies, access, fees, and just how illiquid the venture-like vehicle will prove to be.

Jason and Alex were then joined by Jon Durbin, core contributor at Chutes, and Yash Goenka, co-founder and CEO of Humwork. Chutes is the most valuable Bittensor subnet, focused on aggregating GPUs to offer trustless AI compute. Humwork wants to help bring a human into your agentic workflow to unstick your agent when it runs into a hitch. The show closes with a news lightning round — enjoy!


Timestamps:

0:00 Intro + Plaud AI sponsor read (Jason demos the NotePin S)

2:06 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

3:50 Episode overview: USVC, Chutes, Humwork

7:41 USVC structure: $500 min, no accreditation, quarterly redemptions

10:28 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/twist

11:39 Fee structure breakdown: 1% mgmt fee, ~2.5% net expense ratio

15:41 USVC portfolio: xAI, Anthropic, OpenAI, Crusoe, Vercel

16:17 Strategy: 1/3 emerging managers, 1/3 growth, 1/3 secondaries

19:00 $1B cap and path to expanding the fund

20:33 Vanta - Compliance and security shouldn't be a deal-breaker for startups to win new business. Vanta makes it easy for companies to get a SOC 2 reports fast. Get $1,000 off for a limited time at https://www.vanta.com/twist

28:00 What is sovereign compute? Permissionless GPU networks explained

30:10 Render - Find out why 5 million developers are already using the all-in-one cloud platform, Render. Go to https://render.com/twist and apply for the Render Startup Program to get $500-$100,000 in free credits, depending on your stage and backers.

44:53 Usage history: 160B tokens/day peak, free-to-paid transition

46:41 GPU pricing: from $0.77/hr to $3.50/hr as shortage bites

49:13 DeepSeek censorship demo: Taiwan test on DeepSeek chat

57:27 Permissionless supply curves: Uber/Airbnb analogy for induced demand

59:20 Yash Goenka, co-founder of Humwork (YC S26)

1:00:49 Lightning Round: Ryan Cohen wants to buy eBay — Jason's hot take

1:12:36 Lightning Round: Cerebras IPO update ($27–36B valuation range)

1:14:05 Lightning Round: Spirit Airlines / JetBlue / M&A regulation debate

1:19:10 OFF-DUTY: Star Wars: Maul - Shadow Lord

1:32:57 Alex's OFF-DUTY: Captain of Industry

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Every week, Jason Calacanis dives headfirst into the swirling vortex of Silicon Valley and global tech with This Week in Startups. It’s a direct line to the conversations shaping our digital future, moving far beyond surface-level news. You’ll hear Jason’s unfiltered analysis on everything from market shifts and media trends to the underlying mechanics of building a business, all delivered with a blend of enthusiasm and seasoned skepticism. The core of this podcast, however, lies in the guests. Jason sits down with the very people driving change-founders who have scaled impossible heights, operators managing daily chaos, and investors who spot trends before they become obvious. These conversations are less like formal interviews and more like insider debriefs, pulling back the curtain on real strategies, painful failures, and unexpected successes. For anyone curious about how technology is built, funded, and ultimately changes the world, this series offers a front-row seat. It’s the context behind the headlines, providing a deeper understanding of the forces at play in startups and technology. Tune in for a consistently engaging and insightful look at the ecosystem, straight from someone who lives and breathes it.
Author: Language: en-us Episodes: 100

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