Episode #314: Dr. Sam Shay, MTHFR: Cracking the Genetic Code to Heal

Episode #314: Dr. Sam Shay, MTHFR: Cracking the Genetic Code to Heal

Author: Tim James March 9, 2026 Duration: 1:06:43
Episode #314: Dr. Sam Shay, MTHFR: Cracking the Genetic Code to Heal Hello Health Heroes! In this episode, I sit down with Dr. Sam Shay—a “wounded healer” who grew up with Asperger’s, severe insomnia, anxiety, junk food, bullying, and exhausted parents who tried to medicate symptoms instead of fixing root causes. Today, he’s a chiropractor, acupuncturist, functional medicine doc, genetics expert, and… a neurospicy stand-up comic. And he’s using all of that to flip the script on the lie that “it’s just your genes, there’s nothing you can do.” We break down the difference between genetics and epigenetics—why your genes are the hardware, but your lifestyle and environment are the software running the show. Dr. Sam explains why obsessing over MTHFR is outdated, why inflammation and mitochondrial free radicals should be front of the line, and how your DNA can actually reveal your best diet (keto, paleo, Mediterranean, or higher carb), your trigger foods, and why some people can’t “willpower” their way through cravings. You’ll hear real stories of joint pain, fatigue, water retention, mood swings—and how targeted genetic and lifestyle changes finally moved the needle when “trying everything” didn’t. If you’ve ever felt betrayed by your body or blamed your family tree for your health, this episode will help you forgive your genes, understand your blueprint, and finally take control. Enjoy the show! Love & Light, Coach Tim P.S. If this helped you, please like & subscribe for more inspiration and education to help you become your own best doctor and help heal our world. P.P.S. Connect with Dr. Sam Shay:  For Clients - https://drsamshay.com/ For Doctors - https://fitgenesusa.com/ Tim’s Favorite, HIGHEST QUALITY Health Product Recommendations:Best Detox & Nutrition Supplements: CLICK HEREBest Infrared Saunas & Healing Lamps: Tim’s personal unit - Save $100 CLICK HEREWater Purification/Restructuring System: Book FREE Consult CLICK HEREBest Home Air Purification Unit : Tim’s personal unit CLICK HEREBest Non Toxic Home Building Materials: CLICK HERE  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Tim James has spent years exploring the intersection of practical health and lasting vitality, and he brings those conversations directly to you in Tim James Upgraded. This isn't about fleeting trends or punishing routines; it's a grounded look at the daily choices that compound into a more energetic and resilient life. Each episode breaks down the science and stories behind feeling better, focusing on foundational elements like gut health and metabolic function that influence everything from your waistline to your overall youthfulness. You'll hear from experts and everyday people who have transformed their approach, with Tim acting as your curious guide, asking the questions that cut through the noise. The goal is to make sustainable wellness feel accessible, moving beyond confusion to find what truly works for your body. Tune into this podcast for honest discussions that empower you to upgrade your habits, not with drastic overhauls, but with informed, manageable steps. It’s for anyone who believes that feeling vibrant shouldn't be complicated and that a flat belly is just one visible sign of a much deeper, internal harmony. Join Tim as he demystifies the path to living with more energy every single day.
Author: Language: English Episodes: 100

Tim James Upgraded
Podcast Episodes
Episode #293 Dr. Diane Mueller, Increasing Your Longevity With Sex [not-audio_url] [/not-audio_url]

Duration: 51:47
Episode #293 Dr. Diane Mueller, Increasing Your Longevity With Sex Hello Health Heroes! This week, I had a fascinating conversation with Dr. Diane Mueller, a naturopathic doctor who specializes in helping people live lon…
Episode #292 James Swanwick, How To Live An Alcohol Free Lifestyle [not-audio_url] [/not-audio_url]

Duration: 1:01:33
Episode #292 James Swanwick, How To Live An Alcohol Free Lifestyle Hello Health Heroes! This week, I had an incredible conversation with James Swanwick, a man who built an entire company dedicated to helping people quit…
Episode #291 Arthur Wood, Pain To Cocaine To Consciousness [not-audio_url] [/not-audio_url]

Duration: 1:07:40
Episode #291 Arthur Wood, Pain To Cocaine To Consciousness Hello Health Heroes! This week, I spoke with Arthur Wood who has severe pain in his testicle after a bike accident took him to the doctor. The doctor discovered…
Episode #289 Yerasimos and Joel, Here For The Truth [not-audio_url] [/not-audio_url]

Duration: 57:56
Episode #289 Yerasimos and Joel, Here For The Truth Hello Health Heroes! This week, I spoke with Yerasimos and Joel, the creators to the “Here For The Truth” podcast. Their story on how these two men came together is ano…
Episode #288 Natalie Forstbauer, Heart And Soil Magazine [not-audio_url] [/not-audio_url]

Duration: 1:04:49
Episode #288 Natalie Forstbauer, Heart And Soil Magazine Hello Health Heroes! This week, I spoke with Natalie Forstbauer, the creator and Editor-In-Chief of Heart & Soil Magazine. Their “soil purpose” (Ha Ha) is to provi…
Episode #286 Rachelle Robinett, Making Herbalism Fashionable [not-audio_url] [/not-audio_url]

Duration: 1:07:18
Episode #286 Rachelle Robinett, Making Herbalism Fashionable Hello Health Heroes! This week, I spoke with Rachelle Robinett, currently an herbalist that grew up on a farm in Washington State. She then traveled to New Yor…
Episode #285 W. Wolfe, The Intricacy Of Simplicity [not-audio_url] [/not-audio_url]

Duration: 59:43
Episode #285 W. Wolfe, The Intricacy Of Simplicity Hello Health Heroes! This week, I spoke with W. Wolfe, a freelance artist that took all of his life experiences and was inspired to write a book to help others. The book…
Episode #284 Dan Metcalfe, The Born Superhuman Protocol [not-audio_url] [/not-audio_url]

Duration: 1:05:54
Episode #284 Dan Metcalfe, The Born Superhuman Protocol Hello Health Heroes! This week, I spoke with Dan Metcalfe, who at age nine decided he was going to be a professional athlete but was plagued with asthma and he coul…