Lose the Weight Loss Meds with Dr. James Hill

Lose the Weight Loss Meds with Dr. James Hill

Author: JJ Virgin December 17, 2025 Duration: 51:04
When coming off weight loss medications, how can you prevent your appetite from surging? Also, how can you keep the weight off? In this episode, I explore with Dr. James Hill what really keeps weight off for good. We break down why the strategies that help you lose weight are not the same strategies that help you maintain it, especially in the era of GLP-1 medications. Together, we uncover the science-backed habits and mindset shifts that can help you create a lifestyle that supports your healthiest, happiest self for life. Dr. James Hill is a world-renowned obesity researcher who’s spent over 40 years studying how people lose weight, and more importantly, how they keep it off. He’s the co-founder of the National Weight Control Registry and author of a new book that helps people transition off GLP-1 medications without regaining weight, all delivered with his signature clarity, compassion, and common sense. What you’ll learn: (05:01) Why only about 20% of people keep weight off long-term and why this number may be even lower. (08:19) Why weight loss and weight maintenance require completely different strategies. (11:22) How GLP-1 medications have changed the landscape by helping more people finally reach their goal weight. (12:17) The three pillars of long-term weight maintenance: appetite management, physical activity, and mind state. (14:38) Why pairing high protein intake with resistance training helps protect muscle and improves metabolic health. (22:22) How “mind state” influences your ability to overcome setbacks. (31:26) Why successful maintainers average around 12,000 steps a day and schedule one hour of planned exercise daily. (35:30) The early signs of weight regain. Love the podcast? Here’s what to do: Subscribe to the podcast. Leave a review. Text a screenshot to me at 813-565-2627 and wait for a personal reply because your voice is so important to me. Want to listen to the show completely ad-free? Go to http://subscribetojj.com Click “TRY FREE” and start your ad-free journey today! When you’re ready, enjoy the VIP experience for just $4.99 per month or $49.99 per year (save 17%!) Full show notes (including all links mentioned): https://jjvirgin.com/hill Learn more about your ad choices. Visit megaphone.fm/adchoices

Midlife isn't a crisis; it's a catalyst. On Well Beyond 40, JJ Virgin guides a conversation about rewriting the narrative of aging for women, moving from simply coping to truly thriving. This isn't about chasing youth, but about building a foundation of strength and vitality that makes the coming decades the most rewarding yet. Each episode feels like a direct, practical talk with a trusted expert who cuts through the noise. You'll hear actionable strategies rooted in science, focusing on how nutrition, movement, and mindset intersect uniquely during this life stage. JJ translates complex research into clear steps for refueling your body, managing energy, and cultivating a sense of purpose that goes far beyond the scale. The Well Beyond 40 podcast operates on the principle that knowing *why* something works is just as important as knowing *what* to do. Listeners are invited into a space where questions about metabolic shifts, hormonal balance, sustainable fitness, and intentional beauty are met with evidence-based answers and genuine empathy. It’s a resource for any woman ready to move past generic advice and discover what it means to age with power, confidence, and joy on her own terms. Tune in to reframe your approach and build a life that feels truly well-lived.
Author: Language: English Episodes: 100

Well Beyond 40
Podcast Episodes
Heal Your Gut and Master Menopause with Cynthia Thurlow [not-audio_url] [/not-audio_url]

Duration: 55:46
What if the key to a better night's sleep isn't just a pill, but better gut health? I am so thrilled to welcome my dear friend Cynthia Thurlow, a brilliant nurse practitioner and expert in intermittent fasting, back to t…
Fitness Expert On Most Powerful Predictors on Healthspan [not-audio_url] [/not-audio_url]

Duration: 23:30
Are you focusing on your healthspan while completely neglecting your "strength span"? I have seen so many women hit midlife and feel like their strength and recovery disappeared overnight, but it is often a decline in ce…
Dr. Scott Sherr on Mitochondria, Stress, and Midlife Fatigue [not-audio_url] [/not-audio_url]

Duration: 13:57
What early signs could indicate your metabolism is breaking down? I sat down with Dr. Scott Sherr, a physician focused on health optimization and mitochondrial function, to unpack why so many women feel exhausted despite…
Dr. Jason Fung Explains Why You Are Always Hungry [not-audio_url] [/not-audio_url]

Duration: 49:17
Are you tired of being told that your weight gain is simply a result of a lack of willpower? In this episode, I’m thrilled to welcome back my friend and world-renowned kidney specialist, Dr. Jason Fung, to dive deep into…
Cravings After 40 Are Not a Discipline Problem [not-audio_url] [/not-audio_url]

Duration: 15:22
What if your cravings have nothing to do with discipline? I want you to stop blaming a lack of discipline for your midlife cravings and understand that your body runs on chemistry, not willpower. In this episode, I break…
Mastering Your Internal Symphony [not-audio_url] [/not-audio_url]

Duration: 12:41
Deanna Minich is a nutrition scientist and functional medicine expert who specializes in how food, light, and lifestyle impact whole-body health. She’s known for blending science with practical strategies to help people…
Why Lifting Weights is the Secret to Fat Loss [not-audio_url] [/not-audio_url]

Duration: 23:31
Are you losing muscle instead of fat by over-prioritizing cardio? I'm here to tell you that the common advice to lose weight before lifting is biologically backwards and keeping you frustrated and stuck. In this episode,…
Why Coffee is a Health Superfood with Andrew Salisbury [not-audio_url] [/not-audio_url]

Duration: 42:09
Could your "guilty pleasure" actually be the best thing for your liver health? I’m diving deep into my favorite food group today with Andrew Salisbury, the founder of Purity Coffee, to reveal why your morning brew is act…
What Collagen Actually Does After 30 [not-audio_url] [/not-audio_url]

Duration: 20:24
Are you using collagen incorrectly as a protein replacement? Collagen is one of the most misunderstood supplements in the health world, and I’m breaking down the real science behind it. I explain what collagen actually d…