Can We Prevent Congenital CMV?

Can We Prevent Congenital CMV?

Author: Children's Hospital Colorado November 12, 2024 Duration: 34:44

The most common congenital viral infection in children is cytomegalovirus infection (CMV). Oftentimes the mother will experience little to no symptoms, but the virus can significantly affect the newborn, with outcomes ranging from no symptoms to severe systemic and intercranial complications. What if we could prevent this infection all together with a vaccine? A candidate MRNA vaccine against CMV has elicited promising immune responses to date and is on a pathway towards FDA approval.

To learn more about this treatment, we are joined by one of the nation's leading experts in vaccine development for the prevention of congenital viral disease. Sallie Permar, MD, is the Nancy C. Paduano Professor and Chair of Pediatrics at Weill Cornell Medicine. She serves as pediatrician-in-chief at New York-Presbyterian/Weill Cornell Medical Center. She is also a professor of immunology and microbial pathogenesis at the Weill Graduate School of Medical Sciences.

Some highlights from this episode include: 

  • The scale of impact of congenital CMV in children 
  • Understanding how the virus originates with the mother and affects the baby 
  • Where the CMV vaccine stands in the vaccine development process  
  • Strategies for educating the public and primary care providers on this new treatment   

For more information on Children's Colorado, visit: childrenscolorado.org. 


For those dedicated to the health of children, Charting Pediatrics serves as a vital, ongoing conversation directly from the front lines of pediatric care. Produced by the multidisciplinary experts at Children's Hospital Colorado, this weekly podcast delves into the nuanced realities of modern medicine for young patients. Each episode moves beyond textbook summaries to explore the practical application of groundbreaking research, emerging innovations, and essential educational resources. The discussions are candid, often tackling the complex challenges that clinicians face daily, from evolving treatment protocols to systemic issues within the healthcare community. Now in its eighth season, the program has established itself as a trusted source for physicians, nurses, and allied health professionals seeking to deepen their knowledge and refine their practice. Listening to this podcast feels like gaining direct access to a roundtable of specialists, all focused on a single goal: empowering medical providers with the context and confidence needed to make the best decisions for their patients. The tone is collegial and insightful, transforming the latest evidence and clinical experience into actionable understanding. It’s where the science of pediatrics meets the art of its application, fostering a supportive dialogue for anyone committed to advancing child health.
Author: Language: English Episodes: 100

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