Monitoring Recurrence of Thyroid Cancer by Measuring Thyroglobulin (Tg) and TgAb with Dr. Spencer

Monitoring Recurrence of Thyroid Cancer by Measuring Thyroglobulin (Tg) and TgAb with Dr. Spencer

Author: Philip James interviews top thyroid experts about surgery, nutrition, endoc March 22, 2022 Duration: 18:52
In this episode, Dr. Spencer, Professor of Medicine at University of Southern California, discusses the importance of testing for thyroglobulin-antibodies and thyroglobulin.   Important notes from this interview include:
  • only 10% of nodules are malignant.
  • when getting blood panels each six months, it is very the important to of measure TgAb every time.  
  • consistency is important in blood tests, meaning, use the same laboratory and manufacturer's method every time.
  • the most reliable method of testing TgAb is the machine manufactured by Kronus (RSR) or Roche.  When getting blood tests, be sure to request either of these manufacturers for TgAb results, each of these manufacturers are 100% sensitive.
  • Beckman is  the most commonly used manufacturer, but only is 79% sensitive to TgAb results.
  • always use the same Tg and TgAb methods and the same laboratory.  

Dr. Spencer's major areas of research interest are thyroid physiology and pathology, thyroglobulin and thyroid cancer, immunoassay techniques, thyroid hormone metabolism, and the cost-effective use of thyroid tests. Her current research includes clinical significance of Tg and TgAb in patients with thyroid cancers, parameters for optimizing thyroid hormone suppression of TSH for DTC. Studies on hypothalamic/pituitary mechanisms for regulating TSH, and testing for thyroid dysfunction during pregnancy.

Dr. Spencer earned her PhD from Glasgow University in Scotland. She then went on to complete two fellowships, one in Clinical Biochemistry at Glasgow, and the other at the National Academy of Clinical Biochemistry.  

 

resources:

www.thyroidlab.com/updates


Navigating thyroid health often feels like piecing together a complex puzzle where medical advice, personal experience, and daily well-being intersect. Doctor Thyroid is a space dedicated to that intricate journey, hosted by Philip James. This podcast moves beyond basic explanations to explore the nuanced realities of thyroid conditions, from surgery and radiology to the pivotal roles of nutrition and functional medicine. Philip facilitates conversations with a carefully selected roster of endocrinologists, surgeons, and other top clinical experts, ensuring the dialogue is both authoritative and deeply practical. You’ll also hear from individuals who have personally navigated setbacks and discovered paths to improved health, offering a grounded, relatable perspective. The aim is to provide listeners with a comprehensive toolkit of information-not just the clinical facts, but the applied strategies for enhancing day-to-day life. Whether you’re seeking to understand a new diagnosis, evaluate treatment options, or simply find community in shared experiences, this series offers a thoughtful resource. Tune in for a candid exploration of thyroid care that respects the intelligence of the patient and the expertise of the professionals guiding them.
Author: Language: English Episodes: 100

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