974 - SIBO & Histamine Intolerance

974 - SIBO & Histamine Intolerance

Author: Dr. Michael Ruscio, DC July 7, 2025 Duration: 55:18

Today I'm happy to chat with our patient Leslie who shares her successful journey with histamine intolerance healing. We'll go through how SIBO led to her histamine issues, the connection to low vagus nerve tone, as well as the low histamine diet and treatments such as dao enzymes. Tune in to learn how you can reduce histamine in the body naturally. 

 

Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/

Histamine Intolerance and Diet Guide: https://drruscio.com/guides/get-histamine-intolerance-guide/

 

💊 Products used in Leslie's protocol:

✅Quercetin: 

🔹3 capsules, 1-3 times per day. 

https://store.drruscio.com/products/quercetin?variant=39556224778437

 

✅Resveratrol 500mg Ultra High Potency: 

🔹1 capsule twice daily, may increase to 2 capsules twice daily

https://store.drruscio.com/products/resveratrol?variant=39555978494149

 

✅Vitamin C with Bioflavonoids : 

🔹1-2 tsp or 2 capsules, 1-3x per day

https://store.drruscio.com/products/vitamin-c?variant=39591130595525

 

✅Histamine Digest (DAO enzyme): 

🔹1 prior to meals, may increase to 2 prior to meals

https://store.drruscio.com/products/histamine-digest?variant=42174647435461

 

✅Intestinal Support Formula (ISF): 

🔹5 grams of Immunoglobulin per serving  

🔹Dose range: 5-10 grams per day. 2 scoops = 5 grams.  

🔹May be taken with or without food.

🔹Research shows between 5-10 grams per day to be beneficial

https://store.drruscio.com/products/intestinal-support?variant=29051287765044

https://pubmed.ncbi.nlm.nih.gov/24833942/

 

✅Probiotic Triple Therapy Sticks: 

🔹62 billion CFU per serving

🔹Dose range: 1-3 packets per day 

🔹Probiotics may be taken with or without food 

https://store.drruscio.com/products/triple-therapy-probiotic?variant=40164201922757

 

✅Vagus Nerve Stimulation with VaguStim 

🔹15-30 minutes 1-2x per day 

🔹Follow the user manual and app instructions to get started.

🔹It's important to ensure you're using enough conductive gel in the ears for the device to work effectively. If you're only noticing a faint sensation, even with the device setting fairly high, you're either not using enough gel or the batteries are low. 

🔹It may take up to 1-2 months to observe a benefit from vagus nerve stimulation

https://vagustim.io/collections/home/products/vagus-nerve-stimulation-vns-device-for-individuals

 

🧠Check out our video on vagus nerve stimulation for more information

4 Powerful Vagus Nerve Tools to Rewire Your Nervous System:

https://www.youtube.com/watch?v=Adccokcgo0U



👇 Watch more videos like this 👇 

➡️5 Warning Signs You're Histamine Intolerant:

https://www.youtube.com/watch?v=JPBAd9RzIf4

➡️The Top Diet & Supplements For Healing Histamine Intolerance:

https://www.youtube.com/watch?v=stRThUfzfMM



Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

 

And if you have any questions or topics you would like covered, let me know in the comments!

 

👇Read these next 👇

➡️Vagus Nerve Damage Symptoms, & How to Deal with Them:

https://drruscio.com/vagus-nerve-damage-symptoms/

➡️Everything You Need To Know About Histamine Intolerance:

https://drruscio.com/everything-you-need-to-know-about-histamine-intolerance/

 

Timestamps

00:00 Intro 

02:45 SIBO & histamine intolerance signs

07:30 Histamine intolerance protocol 

10:57 Low histamine diet

16:14 How intolerance happens

18:24 Gut-brain connection

23:32 Probiotics 

25:26 Vagus nerve stimulation

36:21 The importance of mindset

40:31 Key takeaways 

41: 17 Choosing the right healthcare



Featured Studies 

📉Low Serum Diamine Oxidase Activity & Carbohydrate Malabsorption:

https://pubmed.ncbi.nlm.nih.gov/28042564/

📉Disorders of gut-brain interaction in the US:

https://pubmed.ncbi.nlm.nih.gov/36961084/

📉Probiotics for Allergic Rhinitis: https://pubmed.ncbi.nlm.nih.gov/35663980/

📉Symptoms and psychological status in IBS: https://pubmed.ncbi.nlm.nih.gov/36178333/

📉Vagus nerve stimulation & histamine-induced itching: https://pubmed.ncbi.nlm.nih.gov/12105316/

📉Limbic & temporal brain structures & mood enhancing  by vagus nerve stimulation: https://pubmed.ncbi.nlm.nih.gov/17564758/

📉Transcutaneous Auricular Vagus Nerve Stimulation in IBS-C: https://pubmed.ncbi.nlm.nih.gov/39689011/

📉Serum-derived bovine immunoglobulin protein isolate in IBS-D https://pubmed.ncbi.nlm.nih.gov/24833942/



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Instagram - https://www.instagram.com/drruscio/

 

DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g 

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.


Trying to make sense of the latest health trends and research can feel overwhelming. Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare cuts through the noise with grounded, evidence-based conversations. Hosted by clinician and researcher Dr. Michael Ruscio, DC, this podcast explores the practical side of functional health, where complex science is translated into actionable steps you can use. Episodes often start with a curious question-why does one diet work for some but not others, or what does the latest study really mean for everyday health-and follow the evidence where it leads. You’ll hear deep dives into gut health, nutrition, and fitness, balanced with a critical eye that isn’t afraid to debunk popular fads when the data doesn’t support them. The tone is conversational yet precise, reflecting Dr. Ruscio’s dual role as a practicing clinician and a dedicated investigator. Each discussion is built to provide clarity, leaving you with a clearer understanding of how your body works and what might help it work better. It’s important to note that this podcast is for educational and informational purposes. While Dr. Ruscio shares his expertise as a doctor of chiropractic, the content does not constitute personal medical or professional advice. Instead, think of it as a reliable source for thoughtful analysis, helping you have more informed conversations about your own health journey.
Author: Language: English Episodes: 100

Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
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