DR MARIA SOPHOCLES Understanding Vaginal Estrogen & Systemic HRT for Menopause

DR MARIA SOPHOCLES Understanding Vaginal Estrogen & Systemic HRT for Menopause

Author: Tara Garrison October 31, 2025 Duration: 48:46

Dr. Maria Sophocles is as a board-certified gynecologist, sex therapist, leading menopause expert, and a popular TED talk speaker. 

She has taught clinicians this technology on five continents.

Her Princeton clinic and virtual practice serves 30,000 women in the US and globally.

Dr. Sophocles is currently working on a documentary about sex and menopause and developing a health clinic in rural Kenya. 

In this episode, Dr. Sophocles discusses the lack of conversation around women's sexual health, and provides insightful information on hormone replacement therapy around menopause.

 

RESOURCES:

 

CHAPTERS:

0:00 Intro
5:21 Lack of attention in the area of vaginal health
9:52 Shame around sex
11:20 When estrogen goes away
16:40 Systemic HRT
18:00 Bioidentical hormones
21:35 Blood work & pellets
26:00 Dr Sophocles' approach to estrogen & progesterone decline
31:40 What women on HRT can experience
35:20 Separate vaginal and systemic estrogen for cancer patients
37:20 Libido and estrogen, testosterone
40:25 Brain in perimenopause
44:42 Where to learn more from Dr. Maria Sophocles
46:01 "The Bedroom Gap" Book

 

WORK WITH TARA:
Are You Looking for Help on Your Wellness Journey? Here's how Tara can help you:

 

SOCIAL MEDIA: 

 

INSIDE OUT HEALTH PODCAST SPECIAL OFFERS:

☑️ Upgraded Formulas Hair Test Kit Special Offer: https://bit.ly/3YdMn4Z

☑️ Upgraded Formulas - Get 15% OFF Everything with Coupon Code INSIDEOUT15: https://upgradedformulas.com/INSIDEOUT15

☑️ Rep Provisions: Vote for the future of food with your dollar! And enjoy a 15% discount while you're at it with Coupon Code COACHTARA: https://bit.ly/3dD4ZSv

 

If you loved this episode, please leave a review!

Here's how to do it on Apple Podcasts:

  1. Go to Inside Out Health Podcast page: https://podcasts.apple.com/us/podcast/inside-out-health-with-coach-tara-garrison/id1468368093
  2. Scroll down to the 'Ratings & Reviews' section. Tap 'Write a Review' (you may be prompted to log in with your Apple ID). Thank you!

Tara Garrison hosts Inside Out Health, a conversation that starts from the premise that lasting well-being isn't found in a quick fix, but through a more nuanced exploration of our own biology and mindset. This podcast moves beyond surface-level advice, weaving together perspectives from biohacking, intelligent nutrition, purposeful training, and genuine self-development. Each episode is a deep dive with specialists and practitioners, all aimed at untangling the complex connections between physical resilience and mental clarity. You'll hear practical, often unconventional strategies for tuning into your body's signals and building sustainable habits. The dialogue is grounded in the idea that the capacity for a healthier, more vibrant life is an internal discovery process. For anyone curious about moving past generic health trends to understand the personalized mechanics of their own potential, this series offers a thoughtful and investigative space. Tune in to Inside Out Health for a nuanced journey toward what the next level of human health can actually feel like, from the inside out.
Author: Language: English Episodes: 100

Inside Out Health
Podcast Episodes
SOLOCAST: Top 5 Biggest Blocks to Better Body Composition [not-audio_url] [/not-audio_url]

Duration: 56:40
In this episode, Tara breaks down the top five hidden blocks to better body composition—low deep sleep and under‑recovery, poor insulin sensitivity, not enough muscle, overeating "healthy" fats, and the "I come last" min…
KRISTIN WEITZEL Cold, Breath, and Psychedelics for Deep Transformation [not-audio_url] [/not-audio_url]

Duration: 1:08:47
Kristin Weitzel is a force of nature: a master of both strategic brilliance and soulful transformation. With two decades of experience building Fortune 500 brands—she's helmed multi-million-dollar campaigns and orchestra…
DORI LEWIS Psychedelics for Healing & Transformation [not-audio_url] [/not-audio_url]

Duration: 53:59
Dori Lewis is a licensed psychotherapist, clinical supervisor, and co-founder of Elemental Psychedelics. She is also the owner of Reflective Healing Center in Fort Collins, Colorado, a psychotherapy group practice and li…
MIKEL ANDERSON Superior Pain Relief with Nano Technology [not-audio_url] [/not-audio_url]

Duration: 48:04
Mikel Anderson's father was a chiropractor, stress analyst, acupuncturist, and formulator who treated high-profile clients across Europe and the United States. As a child, Mikel traveled country to country, watching cust…
DR JOHN LA PUMA What an Indoor Life is Actually Doing to Your Health [not-audio_url] [/not-audio_url]

Duration: 43:58
John La Puma, MD, ChefMD™ is a two-time New York Times bestselling author, board-certified internist, and professionally trained chef who pioneered Culinary Medicine. He now pioneers EcoMedicine from his small regenerati…
MARGARET CULLEN Upgrade Your Emotional Intelligence [not-audio_url] [/not-audio_url]

Duration: 1:01:46
Margaret Cullen is a licensed psychotherapist and a pioneer in bringing contemplative practices into mainstream settings. She was one of the first ten people to be certified as an MBSR instructor and has taught around th…
DAN PARDI Creatine Explained: Myths vs Science [not-audio_url] [/not-audio_url]

Duration: 59:17
Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he leads education to advance healthspan and peak performance. He's the founder of humanOS.me and host of humanOS Radio, the official podcast of th…