DR MARIA SOPHOCLES Understanding Vaginal Estrogen & Systemic HRT for Menopause

DR MARIA SOPHOCLES Understanding Vaginal Estrogen & Systemic HRT for Menopause

Author: Tara Garrison October 31, 2025 Duration: 48:46

Dr. Maria Sophocles is as a board-certified gynecologist, sex therapist, leading menopause expert, and a popular TED talk speaker. 

She has taught clinicians this technology on five continents.

Her Princeton clinic and virtual practice serves 30,000 women in the US and globally.

Dr. Sophocles is currently working on a documentary about sex and menopause and developing a health clinic in rural Kenya. 

In this episode, Dr. Sophocles discusses the lack of conversation around women's sexual health, and provides insightful information on hormone replacement therapy around menopause.

 

RESOURCES:

 

CHAPTERS:

0:00 Intro
5:21 Lack of attention in the area of vaginal health
9:52 Shame around sex
11:20 When estrogen goes away
16:40 Systemic HRT
18:00 Bioidentical hormones
21:35 Blood work & pellets
26:00 Dr Sophocles' approach to estrogen & progesterone decline
31:40 What women on HRT can experience
35:20 Separate vaginal and systemic estrogen for cancer patients
37:20 Libido and estrogen, testosterone
40:25 Brain in perimenopause
44:42 Where to learn more from Dr. Maria Sophocles
46:01 "The Bedroom Gap" Book

 

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Tara Garrison hosts Inside Out Health, a conversation that starts from the premise that lasting well-being isn't found in a quick fix, but through a more nuanced exploration of our own biology and mindset. This podcast moves beyond surface-level advice, weaving together perspectives from biohacking, intelligent nutrition, purposeful training, and genuine self-development. Each episode is a deep dive with specialists and practitioners, all aimed at untangling the complex connections between physical resilience and mental clarity. You'll hear practical, often unconventional strategies for tuning into your body's signals and building sustainable habits. The dialogue is grounded in the idea that the capacity for a healthier, more vibrant life is an internal discovery process. For anyone curious about moving past generic health trends to understand the personalized mechanics of their own potential, this series offers a thoughtful and investigative space. Tune in to Inside Out Health for a nuanced journey toward what the next level of human health can actually feel like, from the inside out.
Author: Language: English Episodes: 50

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