Catheter Directed Fibrinolysis for Acute PE (HI-PEITHO), NEWS2 Plus Procalcitonin Reduces Mortality (PRONTO)

Catheter Directed Fibrinolysis for Acute PE (HI-PEITHO), NEWS2 Plus Procalcitonin Reduces Mortality (PRONTO)

Author: Stephen Jenkins, MD, Austin Rupp, MD April 7, 2026 Duration: 1:01:27
Extra, extra, read all about it! We have two "NEWS" studies to talk about in this episode (bad pun). Does catheter directed thrombolysis improve outcomes in acute intermediate risk PE? Does adding procalcitonin to NEWS2 screening of ED patients really reduce mortality in patients with suspected sepsis?? The results may surprise you. Biostatistics ninja and critical care physician Dr. Brian Locke joins us to discuss! Ultrasound Facilitated Catheter Directed Fibrinolysis for Acute P...

Keeping up with the flood of new medical research can feel like a full-time job on top of your actual one. That’s where Last Week in Medicine comes in. Hosted by practicing physicians Stephen Jenkins and Austin Rupp, this weekly audio digest is built for clinicians, students, and anyone deeply interested in evidence-based medicine who needs a practical filter for the noise. Instead of spending hours scrolling through tables of contents, you get a curated review of significant findings from top-tier journals like The New England Journal of Medicine, The Lancet, and the JAMA Network, all discussed in a conversational, accessible tone. Each episode breaks down the methodology and clinical implications of recent studies, offering context you won’t find in an abstract. It’s designed to fit into a commute or a workout, transforming dense literature into actionable insight. By tuning in, you’re not just getting updates; you’re hearing two doctors analyze what these advances mean for real-world practice, from hospital medicine to outpatient care. This podcast serves as your ongoing medical education, covering a broad spectrum that includes mental health, fitness, and alternative approaches, all through a rigorous, internal medicine lens. Let Drs. Jenkins and Rupp do the reading, so you can spend your time applying what matters.
Author: Language: en-us Episodes: 67

Last Week in Medicine
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The Apple Heart Study, Colchicine after MI [not-audio_url] [/not-audio_url]

Duration: 23:03
Lots of cardiology to discuss this week with the Apple Heart and COLCOT studies, both published in the New England Journal of Medicine. We also talk about the 3 Wishes Project, the net clinical benefit of oral anticoagul…