Is it useful to measure urine pH? | Masterjohn Q&A Files #90

Is it useful to measure urine pH? | Masterjohn Q&A Files #90

Author: Chris Masterjohn, PhD March 24, 2020 Duration: 6:42

Question: Is it useful to measure urine pH?

The urine pH is telling you the acid burden that your body has been subjected to. It's telling you, you can make an inference about the compensations that your body has had to engage in. You can also make an inference about the limitations of your body in compensating for that because even your urine pH should be buffered. It's not the case that you put a little bit of acid in the urine and then boom your pH is going to go down. It's the case that your body has a whole bunch of systems to buffer even the urine pH as you excrete acids from your body.

The system is, like in your blood, the tiniest, tiniest change in your pH is immediately going to set in motion a change in your breathing rate that is going to cause you to either increase or decrease the exhalation of carbon dioxide in order to adjust the pH of the blood. Then there's going to be a longer-term compensation where you're going to take some of those acids and pee them out. When you pee them out, your kidney is going to buffer those acids in the way of preserving the urine pH.

If your urine pH goes down from 6.5 to 5.5, it tells you that your urine pH is like ten times more acidic, but it doesn't tell you that your blood is ten times more acidic. The critics of using urine pH will point that out. But what it does tell you is that your body has been subjected to a rather enormous acid burden, number one; and number two, that you're even starting to overwhelm your kidney's ability to buffer the urine and prevent the pH of the urine from changing. And so it does tell you about the stress put on the system.

A high potassium intake would be the number one thing that would acutely affect it apart from taking the bicarbonate. By the way, always take bicarbonate on an empty stomach away from food.

This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/09/06/ask-anything-nutrition-march-8-2019

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Access the show notes, transcript, and comments here.

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
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