Did You Know Your Baby’s Sleep & Poop is Tied to Their Gut? with Dr. Stephanie Culler | 244

Did You Know Your Baby’s Sleep & Poop is Tied to Their Gut? with Dr. Stephanie Culler | 244

Author: Trish Ware, RN February 20, 2026 Duration: 26:17
The Birth Experience with Labor Nurse Mama
KidsKids & FamilyCoursesEducationFamilyFitnessHealthHealth & FitnessParenting

What if I told you that 9 out of 10 babies in America are missing key gut microbes right from the start? As a labor nurse who's delivered thousands of little ones and now a proud Gigi, this chat totally rocked my world and got me thinking about my own grandbabies' health.

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I'm thrilled to welcome Stephanie Culler, PhD, co-founder and CEO of Persephone Biosciences. Stephanie's a powerhouse scientist with a PhD in chemical engineering from Caltech, tons of patents in synthetic biology, and a passion for using the gut microbiome to fight disease. Inspired by losing her grandmothers to cancer and her own journey as a first-time mom during COVID, she pivoted from cancer research to baby gut health. She's led the largest U.S. study on infant microbiomes and created groundbreaking products to restore what modern life has stripped away from the gut.

In this episode, we dive deep into:

  1. Why modern babies are missing crucial bifidobacteria - and how it links to allergies, eczema, asthma, and even long-term risks like cancer.
  2. The shocking impact of antibiotics, C-sections, and formula on gut health, and why it's a multi-generational issue.
  3. Stephanie's "aha" moment that shifted her from cancer treatments to preventing issues at the source with Persephone's first-of-its-kind synbiotic.
  4. Signs your baby's gut needs help: fussiness, colic, constipation, diaper rash, poor sleep - and how this product can turn things around fast.
  5. Tips for new moms: Start from day one, even if breastfeeding (mix a smidge into colostrum or on your nipple!), and why it's great for C-section babies too.
  6. Bonus: How this could be a game-changer for adults and pregnant mamas, too.

More from Dr. Stephanie Culler:

Persephone's Daily Synergistic Synbiotic: https://persephone.bio/products/bloom

Visit www.persephone.bio

Follow on Instagram and TikTok: @persephone.bio

Connect with Dr. Stephanie on LinkedIn: https://www.linkedin.com/in/stephanie-culler

Helpful Timestamps:

  1. 00:00 Meet Dr. Stephanie Culler
  2. 01:44 Stephanie’s Story: From Cancer Research to Babies
  3. 05:27 The My Baby Biome Study: The Shocking 9-in-10 Finding
  4. 09:26 Signs of an Off Microbiome + Benefits Seen
  5. 11:16 Why Start From Day One
  6. 15:42 Industrialization & Rising Allergies
  7. 20:41 Practical Tips for Breastfed Babies (No Bottle Needed)
  8. 23:15 C-Section Considerations + Final Takeaways for New Parents

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Produced and Edited by Vaden Podcast Services


Ever find yourself scrolling through endless forums late at night, wondering about the real, unfiltered details of childbirth that no one seems to talk about plainly? The Birth Experience with Labor Nurse Mama is here to change that. Hosted by Trish Ware, RN, this podcast draws directly from her years in the delivery room, where she’s helped bring thousands of newborns into the world. She knows the questions that keep you up at night, from the logistical-like how to effectively push or what Pitocin actually does-to the vulnerable fears about epidurals, VBACs, or those embarrassing but totally normal moments. Trish moves beyond clinical jargon to offer honest, compassionate, and evidence-based insights that feel like a conversation with a trusted friend who’s seen it all. Each episode tackles a specific aspect of pregnancy, labor, and early parenting, like navigating breastfeeding challenges or figuring out newborn care, with the goal of replacing anxiety with practical knowledge. Tuning into this podcast means getting a seasoned labor nurse’s perspective delivered with warmth and a deep understanding of what you’re going through, helping you feel more prepared and empowered for your own journey.
Author: Language: English Episodes: 100

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