New GLP-1 for Alcohol Addiction and IBS, Instagram's AI Fake Crackdown + 5 New Health Tools - 1329

New GLP-1 for Alcohol Addiction and IBS, Instagram's AI Fake Crackdown + 5 New Health Tools - 1329

Author: Chalene Johnson September 2, 2026 Duration: 48:51

Eli Lilly is testing a new GLP-1 called brenipatide in phase three trials, and weight loss isn't even the main focus, researchers are watching it for alcohol use disorder, opioid addiction, bipolar disorder, and IBS. Chalene Johnson also breaks down a new Yale University study on why the hunger hormones ghrelin and leptin roar back the moment someone stops taking a GLP-1.

Then Chalene calls out an Instagram account called Baddie Bethany (also posting as Baddie Betty on Facebook), nearly a million followers and Instagram is rolling out a brand new AI content label. She also flags an AI "Dr. Chen" wellness account blending real health facts with false ones to earn trust.

Plus, five new health devices she's watching, including a toilet sensor called Throne, an AI skin scanner called SkinBit, and a caregiving wearable from the founders of Fitbit.

Topics discussed: Eli Lilly, brenipatide, Zepbound, Yale University, ghrelin, leptin, berberine, Baddie Bethany, Baddie Betty, Dr. Chen, Chen Family Wellness, Carrie Sisson, Instagram, Throne, SkinBit, Prenuvo, 3D Radiology, Eight Sleep, Apple, Fitbit, Lufu, Lindsey Clancy trial.

 

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🚨Questions Chalene Wants Your Thoughts on:

  • Would a GLP-1 built for addiction, not weight, help you?
  • Do you want a button that filters AI content out?
  • What is something you do today that AI will likely be doing for you in five years?

 

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Chapters

  • 00:00:00 — Intro: the Lindsey Clancy trial + episode preview
  • 00:02:15 — Personal update: Penelope's mastectomy surgery and recovery
  • 00:05:39 — Miami penthouse construction saga
  • 00:08:18 — New Yale University study: GLP-1s, hunger hormones, and weight regain
  • 00:12:10 — Losing weight naturally in perimenopause and menopause
  • 00:13:21 — Eli Lilly's new peptide, brenepatide, for addiction and IBS
  • 00:19:03 — Calling out "Baddie Bethany," an AI-generated Instagram account
  • 00:21:31 — Instagram's new AI content labeling policy (Dr. Chen example)
  • 00:28:13 — Instagram's July AI tagging feature backlash
  • 00:31:10 — Health tech roundup: Throne, SkinBit, Eight Sleep, Apple, Fitbit's Lufu Link
  • 00:45:37 — The 2031 journal exercise: predicting the next five years

 


You’ve probably noticed how many voices shout conflicting advice about wellness, leaving you more confused than when you started. The Chalene Show | Diet, Fitness & Life Balance cuts through that noise. Hosted by New York Times Best Selling Author and celebrity fitness trainer Chalene Johnson, this podcast is built on a simple promise: no BS. Chalene is a known diet debunker, and she brings that straight-talk approach to every conversation, whether she’s flying solo or with a guest. The aim is always a tangible return on the time you invest in listening. You’ll hear practical, actionable steps that span far beyond the gym or kitchen. Episodes delve into organization, self-improvement, productivity, and relationships-all the interconnected pieces that create a balanced, healthy life. Chalene’s strategies are deliberately simple, delivered with a relatable humor that makes implementing them feel less like a chore and more like a clear next step. This isn’t about adding more to your to-do list; it’s about working smarter in every area that matters to you. Tuning into this podcast means getting honest, researched guidance that respects your intelligence and your busy schedule. It’s a resource for anyone tired of trends and ready for sustainable change, where the focus is on lasting results over quick fixes. The Chalene Show connects the dots between physical health, mental clarity, and daily execution, offering a comprehensive toolkit for a turbocharged life.
Author: Language: English Episodes: 50

The Chalene Show | Pop Culture, Women's Health, & Fitness
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