New GLP-1 for Alcohol Addiction and IBS, Instagram's AI Fake Crackdown + 5 New Health Tools - 1329

New GLP-1 for Alcohol Addiction and IBS, Instagram's AI Fake Crackdown + 5 New Health Tools - 1329

Author: Chalene Johnson September 2, 2026 Duration: 48:51

Eli Lilly is testing a new GLP-1 called brenipatide in phase three trials, and weight loss isn't even the main focus, researchers are watching it for alcohol use disorder, opioid addiction, bipolar disorder, and IBS. Chalene Johnson also breaks down a new Yale University study on why the hunger hormones ghrelin and leptin roar back the moment someone stops taking a GLP-1.

Then Chalene calls out an Instagram account called Baddie Bethany (also posting as Baddie Betty on Facebook), nearly a million followers and Instagram is rolling out a brand new AI content label. She also flags an AI "Dr. Chen" wellness account blending real health facts with false ones to earn trust.

Plus, five new health devices she's watching, including a toilet sensor called Throne, an AI skin scanner called SkinBit, and a caregiving wearable from the founders of Fitbit.

Topics discussed: Eli Lilly, brenipatide, Zepbound, Yale University, ghrelin, leptin, berberine, Baddie Bethany, Baddie Betty, Dr. Chen, Chen Family Wellness, Carrie Sisson, Instagram, Throne, SkinBit, Prenuvo, 3D Radiology, Eight Sleep, Apple, Fitbit, Lufu, Lindsey Clancy trial.

 

Join Chalene on Patreon her private podcast to hear all the latest on the Penthouse Drama and the Session with a Renowned Pet Psychic  👉chalene.com/more 

 

Book your virtual visit today with MIDI! 👉chalene.com/test

 

🚨Questions Chalene Wants Your Thoughts on:

  • Would a GLP-1 built for addiction, not weight, help you?
  • Do you want a button that filters AI content out?
  • What is something you do today that AI will likely be doing for you in five years?

 

Related Links:

 

To advertise on our podcast, please reach out to thechaleneshow@gmail.com and mention The Chalene Show

 

Connect with me on your fav social platform:

Chapters

  • 00:00:00 — Intro: the Lindsey Clancy trial + episode preview
  • 00:02:15 — Personal update: Penelope's mastectomy surgery and recovery
  • 00:05:39 — Miami penthouse construction saga
  • 00:08:18 — New Yale University study: GLP-1s, hunger hormones, and weight regain
  • 00:12:10 — Losing weight naturally in perimenopause and menopause
  • 00:13:21 — Eli Lilly's new peptide, brenepatide, for addiction and IBS
  • 00:19:03 — Calling out "Baddie Bethany," an AI-generated Instagram account
  • 00:21:31 — Instagram's new AI content labeling policy (Dr. Chen example)
  • 00:28:13 — Instagram's July AI tagging feature backlash
  • 00:31:10 — Health tech roundup: Throne, SkinBit, Eight Sleep, Apple, Fitbit's Lufu Link
  • 00:45:37 — The 2031 journal exercise: predicting the next five years

 


You’ve probably noticed how many voices shout conflicting advice about wellness, leaving you more confused than when you started. The Chalene Show | Diet, Fitness & Life Balance cuts through that noise. Hosted by New York Times Best Selling Author and celebrity fitness trainer Chalene Johnson, this podcast is built on a simple promise: no BS. Chalene is a known diet debunker, and she brings that straight-talk approach to every conversation, whether she’s flying solo or with a guest. The aim is always a tangible return on the time you invest in listening. You’ll hear practical, actionable steps that span far beyond the gym or kitchen. Episodes delve into organization, self-improvement, productivity, and relationships-all the interconnected pieces that create a balanced, healthy life. Chalene’s strategies are deliberately simple, delivered with a relatable humor that makes implementing them feel less like a chore and more like a clear next step. This isn’t about adding more to your to-do list; it’s about working smarter in every area that matters to you. Tuning into this podcast means getting honest, researched guidance that respects your intelligence and your busy schedule. It’s a resource for anyone tired of trends and ready for sustainable change, where the focus is on lasting results over quick fixes. The Chalene Show connects the dots between physical health, mental clarity, and daily execution, offering a comprehensive toolkit for a turbocharged life.
Author: Language: English Episodes: 50

The Chalene Show | Pop Culture, Women's Health, & Fitness
Podcast Episodes
Testosterone for Women Over 40 | Why My Labs Were Wrong - 1318 [not-audio_url] [/not-audio_url]

Duration: 52:39
Testosterone, not GLP-1s, is what finally let Chalene Johnson lose body fat and build real muscle after 40, and she's laying out exactly how in this episode. Chalene explains why her total testosterone always looked norm…
Ageism, Madonna's World Cup Show, and Fillers vs Botox - 1317 [not-audio_url] [/not-audio_url]

Duration: 1:01:37
Chalene Johnson breaks down the Instagram AI feature that had the internet in a panic last week, why deepfake scammers are now stealing real videos and subtly altering someone's voice and appearance to make fake endorsem…
Saturday Spill | Moped Crash, Man Overboard and Cocaine at Lunch [not-audio_url] [/not-audio_url]

Duration: 14:21
Listen to the full 40 minute The Vault episode. Go Directly to this Patreon Episode "Moped Crash, Man Overboard and Cocaine at Lunch" https://www.patreon.com/TheChaleneShow/posts/moped-crash-man-163775955 Picture this...…
Retatrutide vs Ozempic: What the Trials Really Show - 1316 [not-audio_url] [/not-audio_url]

Duration: 1:01:45
Chalene Johnson breaks down retatrutide, the peptide everyone is calling a GLP-3 and an Ozempic killer, cutting through the hype to get to what the science actually says. Eli Lilly's own clinical trials show weight loss…
Jon and Kate Plus 8 Collins Abuse Allegations - 1313 [not-audio_url] [/not-audio_url]

Duration: 51:54
Jon and Kate Plus 8 is back in the news, and it is a lot more complicated than the headlines are making it sound. One of the sextuplets, Colin, has a book coming out in October with abuse allegations against Kate Gosseli…