#523 Hotcakes: Left Atrial Appendage Closure vs AC for Afib, Apixaban vs Rivaroxaban for VTE, Intensive LDL Targeting, GLP1s and Substance Use Disorders, and more

#523 Hotcakes: Left Atrial Appendage Closure vs AC for Afib, Apixaban vs Rivaroxaban for VTE, Intensive LDL Targeting, GLP1s and Substance Use Disorders, and more

Author: The Curbsiders Internal Medicine Podcast April 27, 2026 Duration: 1:06:21

Join us as we review recent practice-changing articles on left atrial appendage closure vs AC for AFib, apixaban vs rivaroxaban for VTE, intensive LDL targeting, GLP1s and substance use disorders, and more! Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Shani Herzig (@ShaniHerzig) Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto).

Claim CME for this episode at curbsiders.vcuhealth.org!

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Credits

  • Written and Hosted by: Rahul Ganatra MD, MPH; Shani Herzig, MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP
  • Cover Art: Rahul Ganatra MD, MPH
  • Reviewer: Emi Okamoto, MD
  • Technical Production: Pod Paste
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

  • Intro, disclaimer
  • Left atrial appendage closure vs anticoagulation in AF
  • Apixaban vs rivaroxaban for VTE
  • Intensive LDL targeting in ASCVD
  • GLP1s and substance use disorders
  • FDA approves Orforglipron
  • E-cigarettes and cancer
  • Early AM blood draws and sleep quality
  • Outro


Sponsor:
FIGS

Go to wearfigs.com to get 20% off during Nurses Week


Sponsor:
Panacea Financial 

If you're about to make the leap into  residency and feeling the financial pressure of that transition, visit PanaceaFinancial.com/curbsiders today


Sponsor:
MasterClass 

Right now, as a listener of this show, you get at least 15% off any annual membership at MASTERCLASS.com/CURB.


Tune in to The Curbsiders Internal Medicine Podcast for a direct line to practical clinical knowledge and the ever-evolving art of patient care. This isn't a dry lecture series; it's a dynamic conversation among practicing physicians who break down complex topics into actionable insights you can use. Each episode delves into the nuances of internal medicine, from managing common chronic conditions to interpreting the latest guidelines and navigating diagnostic dilemmas. You'll hear honest discussions about challenges at the bedside, evidence-based debates, and expert interviews that go beyond textbook summaries to reveal how medicine works in the real world. The podcast serves as both a continuing education resource and a professional companion, offering thoughtful analysis and clinical pearls that resonate whether you're a seasoned hospitalist, a resident in training, or a primary care provider. The focus is consistently on deepening understanding and improving daily practice, making the rounds or the clinic day feel a little less daunting and a lot more informed. Listen for a blend of curiosity, camaraderie, and a genuine commitment to mastering the craft of medicine, all delivered through engaging dialogue that feels like consulting with a trusted colleague.
Author: Language: English Episodes: 100

The Curbsiders Internal Medicine Podcast
Podcast Episodes
#528 Hospital Addiction Medicine 3.0 with Dr. Maggie Lowenstein [not-audio_url] [/not-audio_url]

Duration: 1:18:55
Become the Medetomi-Dean of AdmissionsStep up your hospital addiction medicine game by learning to troubleshoot methadone dose confirmations/missed doses and understanding how medetomidine’s emergency in the drug supply…
#527 Oncology Potpourri for the Hospitalist [not-audio_url] [/not-audio_url]

Duration: 59:38
Malignant Bowel Obstruction, VTE and Goals of CareMaster malignant bowel obstruction, cancer-associated thrombosis, and goals-of-care conversations in hospitalized patients with advanced cancer. Learn practical approache…
#525: Multi-Cancer Early Detection Testing [not-audio_url] [/not-audio_url]

Duration: 48:58
Cut through the hype of Multi-Cancer Early Detection (MCED) tests and learn how to counsel patients on the real-world utility, false-positive risks, and the "stage shift" debate of these emerging blood assays. We are joi…
#524 SHM Converge 2026–Recap [not-audio_url] [/not-audio_url]

Duration: 1:45:56
We go so that you want to go next year!Stay current with updates in hospital medicine from SHM Converge 2026 in Nashville, TN. Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spoti…
#522: Healthy Aging with Dr. Elizabeth Eckstrom [not-audio_url] [/not-audio_url]

Duration: 1:19:56
Join us as we explore practical, evidence-based strategies to help patients age with strength and confidence, and navigate the transition into retirement. We’re joined by Dr. Elizabeth Eckstrom (Oregon Health & Science U…
#521 Tales of the Pelvis [not-audio_url] [/not-audio_url]

Duration: 1:19:53
Gain an insider’s perspective on the techniques of pelvic floor physical therapy. Learn when to refer, what to expect and what can be gained from working with your friendly neighborhood pelvic floor PT specialist. We’re…
#520: Healthspan Medicine, A Practical Approach [not-audio_url] [/not-audio_url]

Duration: 1:19:36
How do we help patients improve health span without letting wearables, biomarkers, and wellness trends take over the conversation? Learn how to think about CGMs in patients without diabetes, how to interpret early cardio…
#519 Mild Autonomous Cortisol Secretion [not-audio_url] [/not-audio_url]

Duration: 1:13:57
Become a master of cortisol and learn how to identify and treat a common condition in patients with adrenal tumors! Join us as we learn about mild autonomous cortisol secretion (MACS) with Dr. Irina Bancos (@irinabancos)…