#523 Hotcakes: Left Atrial Appendage Closure vs AC for Afib, Apixaban vs Rivaroxaban for VTE, Intensive LDL Targeting, GLP1s and Substance Use Disorders, and more

#523 Hotcakes: Left Atrial Appendage Closure vs AC for Afib, Apixaban vs Rivaroxaban for VTE, Intensive LDL Targeting, GLP1s and Substance Use Disorders, and more

Author: The Curbsiders Internal Medicine Podcast April 27, 2026 Duration: 1:01:49

Join us as we review recent practice-changing articles on left atrial appendage closure vs AC for AFib, apixaban vs rivaroxaban for VTE, intensive LDL targeting, GLP1s and substance use disorders, and more! Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Shani Herzig (@ShaniHerzig) Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto).

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Credits

  • Written and Hosted by: Rahul Ganatra MD, MPH; Shani Herzig, MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP
  • Cover Art: Rahul Ganatra MD, MPH
  • Reviewer: Emi Okamoto, MD
  • Technical Production: Pod Paste
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

  • Intro, disclaimer
  • Left atrial appendage closure vs anticoagulation in AF
  • Apixaban vs rivaroxaban for VTE
  • Intensive LDL targeting in ASCVD
  • GLP1s and substance use disorders
  • FDA approves Orforglipron
  • E-cigarettes and cancer
  • Early AM blood draws and sleep quality
  • Outro


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Tune in to The Curbsiders Internal Medicine Podcast for a direct line to practical clinical knowledge and the ever-evolving art of patient care. This isn't a dry lecture series; it's a dynamic conversation among practicing physicians who break down complex topics into actionable insights you can use. Each episode delves into the nuances of internal medicine, from managing common chronic conditions to interpreting the latest guidelines and navigating diagnostic dilemmas. You'll hear honest discussions about challenges at the bedside, evidence-based debates, and expert interviews that go beyond textbook summaries to reveal how medicine works in the real world. The podcast serves as both a continuing education resource and a professional companion, offering thoughtful analysis and clinical pearls that resonate whether you're a seasoned hospitalist, a resident in training, or a primary care provider. The focus is consistently on deepening understanding and improving daily practice, making the rounds or the clinic day feel a little less daunting and a lot more informed. Listen for a blend of curiosity, camaraderie, and a genuine commitment to mastering the craft of medicine, all delivered through engaging dialogue that feels like consulting with a trusted colleague.
Author: Language: English Episodes: 50

The Curbsiders Internal Medicine Podcast
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