Millions of Women Stopped Taking Hormones Because of a Misread Study | Dr. Sharon Malone

Millions of Women Stopped Taking Hormones Because of a Misread Study | Dr. Sharon Malone

Author: Dr. Mark Hyman May 27, 2026 Duration: 1:27:37
For far too long, many women have been told their symptoms were normal, exaggerated, or simply something they had to live with—treated as isolated problems instead of part of a much larger hormonal transition happening inside the body. On this episode of The Dr. Hyman Show, I’m joined by Dr. Sharon Malone, host of The Second Opinion podcast and Chief Medical Advisor at Alloy Women’s Health. We discuss how menopause and hormone therapy became so misunderstood, the real story behind the Women’s Health Initiative study, and why a more individualized, prevention-focused approach to women’s health is long overdue. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We explore: Why so many women enter perimenopause completely unprepared—and how symptoms can begin years before menopause officially starts What the Women’s Health Initiative actually found, and how one medical narrative reshaped women’s healthcare for decades How menopause affects far more than reproduction, including the brain, heart, sleep, metabolism, and bone health What you should know about hormone therapy today, including timing, individualized treatment, and understanding risk in context The daily habits that still matter most for healthy aging, whether or not you choose hormone therapy Midlife health should never be reduced to “just deal with it.” The more women understand what’s happening inside their bodies, the earlier they can take steps to protect their long-term health and quality of life. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - ⁠Click Here⁠ Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Paleovalley, Pique, Perfect Amino, Rho, Sunlighten and BIOptimizers. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. (0:00) Introduction, survey on hormone use, and Dr. Sharon Malone’s expertise   (4:04) Importance of women's health research and historical neglect   (5:35) Lack of education and preparation for menopause   (6:28) Societal and historical biases in women's health   (9:05) Observational studies vs. randomized controlled trials   (13:30) Life cycles, hormonal changes, and stages in women   (19:26) Detailed stages of hormonal changes and perimenopause   (23:00) Misdiagnosis and definition of menopause   (25:02) The term "postmenopausal" and its significance   (26:34) Impact of menopause on organ systems and major symptoms   (31:19) Lifestyle factors and hormone therapy options   (39:25) Black box warning, Women’s Health Initiative, and therapy timing   (45:00) Women's Health Initiative findings and breast cancer risk   (47:57) Reinterpreting breast cancer risk and black box warning   (53:21) Personalized hormone therapy and clinical diagnosis   (59:55) Importance of estrogen and bioidentical vs. synthetic hormones   (1:03:35) Addressing sexual health and testosterone use for women   (1:08:05) FDA-approved peptides for women’s arousal disorder   (1:09:57) Long-term benefits of hormone therapy   (1:12:43) Early menopause, hormone therapy, and health impacts   (1:15:07) Estrogen’s role in brain health and dementia prevention   (1:16:22) Alzheimer’s risk in women and hormonal 

Hosted by physician and functional medicine pioneer Dr. Mark Hyman, The Dr. Hyman Show is a conversation about reclaiming your well-being. Each episode digs into the interconnected systems that shape our health, moving beyond symptom management to address foundational causes. You’ll hear detailed discussions on nutrition, the roots of chronic disease, mental health strategies, and the science of longevity, all framed through a functional medicine lens. Dr. Hyman engages with leading experts and thinkers to challenge conventional wisdom on food policy and prevention, offering a practical and often provocative perspective. This podcast serves as a resource for anyone feeling lost in a healthcare system that can overlook root causes, providing actionable knowledge to make informed daily choices. Tune in for a deep, evidence-based exploration of how our bodies truly work, empowering you to reimagine your personal health potential through informed dialogue and discovery.
Author: Language: English Episodes: 100

The Dr. Hyman Show
Podcast Episodes
Why Your Cholesterol Is High—and How to Start Fixing It in 10 Days [not-audio_url] [/not-audio_url]

Duration: 23:46
High cholesterol is one of the most common reasons people are told they’re at risk for heart disease. But what if cholesterol isn’t the root problem? What if it’s actually a signal of deeper metabolic dysfunction—and foc…
Are You Secretly Dehydrated? Why a 1% Drop Kills Your Focus and Mood [not-audio_url] [/not-audio_url]

Duration: 18:32
Hydration affects far more than thirst. Even mild dehydration can impact your focus, memory, mood, energy, and overall brain performance—yet most people walk through the day without realizing they’re under-hydrated. The…
The 5 Root Causes of Autoimmune Disease (And How to Start Healing) [not-audio_url] [/not-audio_url]

Duration: 27:08
Autoimmune disease is often treated as something random, lifelong, and out of your control. But what if it’s not your body malfunctioning—what if it’s your immune system responding exactly the way it’s designed to, to so…
The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin [not-audio_url] [/not-audio_url]

Duration: 1:12:53
We tend to think of heart disease, cancer, and Alzheimer’s as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose r…
6 Root Causes of Migraines (And How to Fix Them) [not-audio_url] [/not-audio_url]

Duration: 26:40
Migraines aren’t just headaches and if you’ve ever had one, you know how debilitating they can be. But they’re not random, and they’re not just genetic. Migraines are a signal that something deeper is out of balance in y…