#114: Mindfulness, Medicine & the Biology of Stress - Dr. Craig Hassed

#114: Mindfulness, Medicine & the Biology of Stress - Dr. Craig Hassed

Author: FitMind: Neuroscience, Meditation & Mental Fitness Training June 17, 2026 Duration: 1:03:02

Mindfulness, Medicine & the Biology of Stress explores how meditation can change our relationship to stress, support the body's natural healing systems, and help us live with more presence, compassion, and ease.

In this episode of The FitMind Podcast, we sit down with Craig Hassed, MD, physician, educator, and mindfulness expert, to examine the science and practice of mind-body medicine. Drawing from decades of clinical work, teaching, and contemplative practice, Craig explains how chronic stress creates physiological wear and tear in the body, known as allostatic load, and why learning to return to the present moment can have effects far beyond feeling calmer.

The conversation explores how mindfulness may influence inflammation, immune function, gene expression, and biological aging, including research on telomeres and the body's stress circuitry. Craig also discusses why informal mindfulness in daily life may be just as important as formal meditation practice, especially when we are caught in worry, pressure, or mental projections about the future.

Topics include:

  • How mindfulness became part of the medical curriculum at Monash University
  • Why chronic stress creates wear and tear on the body
  • What allostatic load means for health and aging
  • How meditation may affect inflammation, immunity, and gene expression
  • The relationship between mindfulness and telomeres
  • Why presence can improve focus, performance, and flow
  • The difference between empathy, empathic distress, and compassion
  • Why compassion may protect against burnout
  • How mindfulness can support doctors, patients, students, and everyday life
  • The question of consciousness and whether it may be more fundamental than matter

A practical and wide-ranging conversation for anyone interested in the medical science of mindfulness, the biology of stress, or how contemplative practice can support resilience, compassion, and human flourishing.

---

Liam's book, Fit Mind, is now available! You can pick up a copy and learn more at fitmind.org/book.

FitMind Neuroscience-Based App: http://bit.ly/afitmind

Website: www.fitmind.org

---

Show Notes

0:00 | Introduction to Dr. Craig Hassed
3:23 | Discovering meditation without a teacher
9:18 | Bringing mindfulness into clinical medicine
10:21 | Teaching mindfulness to medical students
15:10 | How chronic stress affects the body
15:56 | Understanding allostatic load
20:57 | Epigenetics, inflammation, and immune function
22:42 | Meditation, telomeres, and biological aging
26:17 | How much meditation is enough?
29:18 | Formal practice vs. mindfulness in daily life
31:17 | The growth of mindfulness research
36:54 | The ESSENCE model of health
38:56 | Choosing the right meditation practice
41:47 | How the mind creates unnecessary stress
45:21 | Mindfulness, performance, and flow states
51:21 | Mindfulness education and human flourishing
52:40 | Technology, isolation, and genuine connection
1:00:43 | Empathy, empathic distress, and compassion
1:01:42 | Why compassion may protect against burnout
1:06:16 | Is consciousness more fundamental than matter?
1:07:10 | Can consciousness be scientifically measured?
1:08:33 | Craig's daily practice and rapid-fire questions
1:09:15 | Final thoughts


What if the most impactful training you could do wasn't for your body, but for your mind? The FitMind Podcast: Mental Fitness, Neuroscience & Psychology explores that very idea, moving beyond simple self-help to examine the tangible science behind cognitive well-being. Host Liam McClintock, founder of FitMind, sits down with an eclectic mix of world-class experts-neuroscientists mapping the brain's pathways, psychologists unpacking behavioral patterns, Buddhist monks with millennia of contemplative wisdom, and elite athletes who apply mental discipline at the highest levels. Their conversations delve into practical applications of mindfulness meditation, the principles of Stoicism, emerging brain technologies, and the pursuit of sustainable productivity and happiness. This isn't just theoretical discussion; it's a deep dive into actionable strategies, grounded in research, aimed at strengthening your mental resilience. Each episode serves as a session for your cognitive toolkit, reflecting the core belief that understanding and training the mind is our most vital frontier. Tune in to this podcast for a thoughtful, evidence-based guide to building a healthier, more focused, and resilient inner life.
Author: Language: English Episodes: 50

The FitMind Podcast: Mental Fitness, Neuroscience & Psychology
Podcast Episodes
#95: Mental Wellness & Monk Training - Andrew Litchy, ND [not-audio_url] [/not-audio_url]

Duration: 1:47:13
In this episode, Dr. Andrew Litchy recounts his journey from life as a monk to becoming a naturopathic doctor. He shares his insights on how meditation helped him manage ADHD and how it has become integral to both his pe…
#94: Exploring Consciousness & Deep Awareness - Doug Kraft [not-audio_url] [/not-audio_url]

Duration: 59:43
How does the mind shape our reality? What happens when the conceptual mind turns off? The answers might be found in the depths of meditation. Doug Kraft has delved into the complexities of the mind from various perspecti…
#91: The Science of Creativity & Imagination - Anna Abraham, PhD [not-audio_url] [/not-audio_url]

Duration: 1:02:21
Dr. Anna Abraham is a psychologist and neuroscientist who investigates creativity and how we can optimize this key trait. She's also a leading scholar on the study of human imagination. On this episode, we discuss the ke…
#90: Master of Sleep - Nick Littlehales [not-audio_url] [/not-audio_url]

Duration: 50:22
Nick Littlehales has been an elite sport recovery coach for nearly a quarter-century and is the bestselling author of Sleep: The Myth of 8 Hours, the Power of Naps... and the New Plan to Recharge Your Body and Mind. On t…
#89: Consciousness, Perception & Reality - Donald Hoffman, PhD [not-audio_url] [/not-audio_url]

Duration: 50:56
Donald Hoffman, PhD is a cognitive scientist and author of The Case Against Reality: Why Evolution Hid the Truth from Our Eyes. He is currently a professor at UC Irvine, where he studies consciousness, visual perception…
#88: Profound States of Mind - Andrew Holecek [not-audio_url] [/not-audio_url]

Duration: 1:07:45
Andrew Holecek is an author and meditation teacher with decades of intensive practice experience, including a 3-year silent retreat in the Tibetan tradition. Andrew's work combines ancient wisdom with modern science. We…
#87: The Future of the Brain - Miguel Nicolelis, MD, PhD [not-audio_url] [/not-audio_url]

Duration: 1:03:43
Miguel Nicolelis, MD, PhD is a Brazilian neuroscientist and physician famous for his pioneering work in the field of brain-machine interface (BMI) technology. Dr. Nicolelis's extensive research with brain-machine interfa…
#86: The Science of Spontaneity - Edward Slingerland, PhD [not-audio_url] [/not-audio_url]

Duration: 45:32
Edward Slingerland, PhD, is a Professor of Philosophy and Associate Member in the Asian Studies and Psychology Departments at the University of British Columbia. He's an expert on the cognitive science of ancient philoso…