#114: Mindfulness, Medicine & the Biology of Stress - Dr. Craig Hassed

#114: Mindfulness, Medicine & the Biology of Stress - Dr. Craig Hassed

Author: FitMind: Neuroscience, Meditation & Mental Fitness Training June 17, 2026 Duration: 1:03:02

Mindfulness, Medicine & the Biology of Stress explores how meditation can change our relationship to stress, support the body's natural healing systems, and help us live with more presence, compassion, and ease.

In this episode of The FitMind Podcast, we sit down with Craig Hassed, MD, physician, educator, and mindfulness expert, to examine the science and practice of mind-body medicine. Drawing from decades of clinical work, teaching, and contemplative practice, Craig explains how chronic stress creates physiological wear and tear in the body, known as allostatic load, and why learning to return to the present moment can have effects far beyond feeling calmer.

The conversation explores how mindfulness may influence inflammation, immune function, gene expression, and biological aging, including research on telomeres and the body's stress circuitry. Craig also discusses why informal mindfulness in daily life may be just as important as formal meditation practice, especially when we are caught in worry, pressure, or mental projections about the future.

Topics include:

  • How mindfulness became part of the medical curriculum at Monash University
  • Why chronic stress creates wear and tear on the body
  • What allostatic load means for health and aging
  • How meditation may affect inflammation, immunity, and gene expression
  • The relationship between mindfulness and telomeres
  • Why presence can improve focus, performance, and flow
  • The difference between empathy, empathic distress, and compassion
  • Why compassion may protect against burnout
  • How mindfulness can support doctors, patients, students, and everyday life
  • The question of consciousness and whether it may be more fundamental than matter

A practical and wide-ranging conversation for anyone interested in the medical science of mindfulness, the biology of stress, or how contemplative practice can support resilience, compassion, and human flourishing.

---

Liam's book, Fit Mind, is now available! You can pick up a copy and learn more at fitmind.org/book.

FitMind Neuroscience-Based App: http://bit.ly/afitmind

Website: www.fitmind.org

---

Show Notes

0:00 | Introduction to Dr. Craig Hassed
3:23 | Discovering meditation without a teacher
9:18 | Bringing mindfulness into clinical medicine
10:21 | Teaching mindfulness to medical students
15:10 | How chronic stress affects the body
15:56 | Understanding allostatic load
20:57 | Epigenetics, inflammation, and immune function
22:42 | Meditation, telomeres, and biological aging
26:17 | How much meditation is enough?
29:18 | Formal practice vs. mindfulness in daily life
31:17 | The growth of mindfulness research
36:54 | The ESSENCE model of health
38:56 | Choosing the right meditation practice
41:47 | How the mind creates unnecessary stress
45:21 | Mindfulness, performance, and flow states
51:21 | Mindfulness education and human flourishing
52:40 | Technology, isolation, and genuine connection
1:00:43 | Empathy, empathic distress, and compassion
1:01:42 | Why compassion may protect against burnout
1:06:16 | Is consciousness more fundamental than matter?
1:07:10 | Can consciousness be scientifically measured?
1:08:33 | Craig's daily practice and rapid-fire questions
1:09:15 | Final thoughts


What if the most impactful training you could do wasn't for your body, but for your mind? The FitMind Podcast: Mental Fitness, Neuroscience & Psychology explores that very idea, moving beyond simple self-help to examine the tangible science behind cognitive well-being. Host Liam McClintock, founder of FitMind, sits down with an eclectic mix of world-class experts-neuroscientists mapping the brain's pathways, psychologists unpacking behavioral patterns, Buddhist monks with millennia of contemplative wisdom, and elite athletes who apply mental discipline at the highest levels. Their conversations delve into practical applications of mindfulness meditation, the principles of Stoicism, emerging brain technologies, and the pursuit of sustainable productivity and happiness. This isn't just theoretical discussion; it's a deep dive into actionable strategies, grounded in research, aimed at strengthening your mental resilience. Each episode serves as a session for your cognitive toolkit, reflecting the core belief that understanding and training the mind is our most vital frontier. Tune in to this podcast for a thoughtful, evidence-based guide to building a healthier, more focused, and resilient inner life.
Author: Language: English Episodes: 50

The FitMind Podcast: Mental Fitness, Neuroscience & Psychology
Podcast Episodes
#84: The Brain of a Mental Olympian - Elena Antonova, PhD [not-audio_url] [/not-audio_url]

Duration: 1:06:26
Dr. Elena Antonova is a neuroscientist and senior lecturer in psychology at Brunel University London. Her research focuses on the effects of long-term mindfulness meditation practice in the hope of promoting mental wellb…
#83: Origins of the Mind - Antonio Damasio, MD, PhD [not-audio_url] [/not-audio_url]

Duration: 48:08
Dr. Antonio Damasio is a neurologist, psychologist and best-selling author. He's the Founder & Director of the Brain and Creativity Institute, which researches human emotions, memory, communication, and decision-making,…
#82: Sleep & Dreams - Sidarta Ribeiro, PhD [not-audio_url] [/not-audio_url]

Duration: 57:23
Dr. Sidarta Ribeiro is an award-winning neuroscientist, author, and Founder of the Brain Institute at Universidade Federal do Rio Grande do Norte in Brazil, where he is also a professor of neuroscience. In this episode,…
#81: Mind Control & Brain-Computer Interfaces - Ramses Alcaide, PhD [not-audio_url] [/not-audio_url]

Duration: 46:28
Ramses Alcaide, PhD is an electrical engineer, neuroscientist, and CEO of Neurable, an innovative brain-computer interface company. At Neurable, he is the inventor and primary developer of a brain-computer interface tech…
#80: The Power of Focus - Amishi Jha, PhD [not-audio_url] [/not-audio_url]

Duration: 49:59
Dr. Amishi Jha is a neuroscientist and professor of psychology at the University of Miami. She's the Director and Co-Founder of Contemplative Neuroscience for the Mindfulness Research and Practice Initiative. Dr. Jha lea…
#79: Pain & Placebo - Apkar V. Apkarian, PhD [not-audio_url] [/not-audio_url]

Duration: 52:54
Apkar V. Apkarian, PhD is a professor of physiology, anesthesiology, and physical medicine and rehabilitation at Northwestern University's Feinberg School of Medicine. He has been studying pain for more than two decades…
#78: Neuroscience, Consciousness & Nonduality - James Cooke, PhD [not-audio_url] [/not-audio_url]

Duration: 55:51
Dr. James Cooke is a neuroscientist, writer and speaker, focused on consciousness, meditation, psychedelic states, and science. He studied Experimental Psychology and completed his PhD in Neuroscience at Oxford Universit…
#77: The Science of Compassion - Shauna Shapiro, PhD [not-audio_url] [/not-audio_url]

Duration: 41:23
Shauna Shapiro, PhD, is a clinical psychologist, bestselling author, and an expert in mindfulness and self-compassion. She has spent two decades studying the benefits of mindfulness and compassion. Her TEDx Talk on this…
#76: Peak Performance Mindset - Elliot Roe [not-audio_url] [/not-audio_url]

Duration: 48:10
Elliot Roe is a leading expert in mindset optimization for high performers. In just the last 3 years his poker clients have won over $150,000,000 and nearly every major tournament title, including the World Series of Pok…
#75: The Stoic Philosophy - Massimo Pigliucci, PhD [not-audio_url] [/not-audio_url]

Duration: 1:02:20
Dr. Massimo Pigliucci is Professor of Philosophy at the City College of New York, former co-host of the Rationally Speaking Podcast, and one of the most influential modern Stoics. He's published several books including H…