Kiran Krishnan on How to Build a Resilient Microbiome

Kiran Krishnan on How to Build a Resilient Microbiome

Author: Kriben Govender November 3, 2019 Duration: 1:09:33
Food Scientist and Registered Nutritionist, Kriben Govender (Honours Degree in Food Science & Technology) has an insightful conversation with Chief Scientific Officer of Microbiome Labs, Kiran Krishnan on How to build a resilient microbiome, metabolic endotoxemia (leaky gut), the negative impact of lipopolysaccharides (LPS), the diabetes pandemic, probiotics for optimal health, spore-based probiotics, postbiotics, butyrate and acne control, keystone bacteria in the gut and much more   
 
 
Bio: 
 
Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa.  He is currently involved in 9 novel human clinical trials on probiotics and the human microbiome. Kiran is also on the Scientific Advisory Board for 5 companies in the industry. Kiran offers his extensive knowledge and practical application of the latest science on the human microbiome as it relates to health and wellness.
 
 
 
Topics discussed:
 
  • Kiran's origin story
  • What does good gut health look like?
  • The concept of "resilience" in gut health
  • What about different dietary regimes like paleo, vegan, carnivore etc?
  • Human evolution of omnivores
  • Gut sensitivity in the modern world
  • How to foster resilience
  • The concept of "Holobiome"
  • Living in an antibiotic laden world
  • Exposure from personal care products
  • Maximising exposure to environmental microbes
  • Allergies, Asthma and the microbiome
  • Diversity of diet like our ancestors
  • Spore based bacteria
  • Metabolic endotoxemia (leaky gut) and chronic disease 
  • Lipopolysaccharides, Gram-Positive and Gram-Negative Bacteria
  • Sepsis and bacteraemia signalling
  • LPS and Chronic inflammation, Rheumatoid Arthritis, Anxiety and Depression, Alzheimer's 
  • LPS toxicity and bacterial types
  • LPS and Diabetes Risk
  • LPS mechanism on impairing blood sugar modulation
  • The impact of C-section on gut microbiome composition 
  • Antibiotics and the microbiome
  • What is a probiotic organism?
  • Where do probiotics come from?
  • The origin of Spore based probiotics
  • What are spore-based bacteria?
  • The gastric barrier, bile salts and pancreatic enzymes 
  • Short Chain Fatty Acids, Postbiotics and Metformin
  • Butyrate and insulin sensitivity
  • Butyrate and acne control 
  • Oligosaccharide based prebiotics- FOS, GOS, XYLO
  • Keystone Species in the Microbiome: Akkermansia, Faecalibacterium, Bifidobacteria, Ruminocococus 
  • The benefits of dead bacteria (biological response modifiers), BLP1, Micro RNA, Microvesicles 
  • Intra- kingdom communication and gene expression
  • The importance of subspecies classification and associated health benefits
  • The science of postbiotics and AMUC 
  •  Megasporebiotic and Leaky Gut
 
 
Brought to you by:
 
Nourishme Organics- The Gut Health Superstore
 
Check out our range of clinically proven probiotic supplements including Microbiome Labs Megasporebiotic:
 
 
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Connect with Kiran Krishnan
 
 
 
 
Connect with Kriben Govender: 
 
Gut Health Gurus Facebook Group: https://www.facebook.com/groups/nourishmeorganics/
Deuterium Depletion Support Facebook Group: https://www.facebook.com/groups/347845406055631/
 
Download links
 
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Kriben Govender's journey is a testament to how personal crisis can lead to profound discovery. After a period where his life unraveled through professional bullying, personal loss, and deep isolation, he found a lifeline not in abstract concepts, but in the very real science of the microbiome. As a Food Scientist and founder of Nourishme Organics, Kriben now channels that hard-won perspective into The Gut Health Gurus Podcast. Here, conversations move beyond dry dietary advice to explore the tangible connections between our digestive system and everything from mental resilience to physical fitness. Each episode feels like a candid discussion, unpacking how nurturing gut health can fundamentally alter one's wellbeing. You'll hear from a range of voices-scientists, practitioners, and people with lived experience-all grounded in Kriben's own understanding that true health often starts from within. This isn't about quick fixes; it's about building a sustainable, informed relationship with your body. Tune in for a podcast that blends evidence-based nutrition with the very human stories behind the science, offering a compassionate and practical guide to taking control of your health from the inside out.
Author: Language: English Episodes: 70

The Gut Health Gurus Podcast
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