Anne Child on Marfan syndrome and love at first sight

Anne Child on Marfan syndrome and love at first sight

Author: BBC Radio 4 July 2, 2024 Duration: 28:35

Marfan syndrome is a genetic disorder that makes renders the body’s connective tissues incredibly fragile; this can weaken the heart, leading to potentially fatal aneurysms. What’s more, anyone with the condition has a 50/50 chance of passing it on to their children.

Dr Anne Child is a clinical geneticist who’s dedicated her professional life to finding answers and solutions for people affected by Marfan’s.

Born in Canada, she met her British future-husband while working in Montreal in a case she describes as "love at first sight" - and in the 1970s she relocated her life to the UK.

There, an encounter with a Marfan patient she was unable to help set Anne on a career path for life. She subsequently established the team that discovered the gene responsible for Marfan's, and founded the Marfan Trust to drive further research. Since then, life expectancy for those with the condition has jumped from 32 years old, to over 70.

Speaking to Professor Jim Al-Khalili, Anne shares how she and her team achieved this remarkable turnaround.

Presented by Jim Al-Khalili Produced by Lucy Taylor


Hosted by physicist and author Professor Jim Al-Khalili, The Life Scientific offers a rare and intimate glimpse into the minds shaping our world. Each conversation moves beyond the standard lecture or interview, weaving together personal history with groundbreaking ideas. You’ll hear how childhood curiosity, unexpected setbacks, and moments of sheer luck have steered the careers of some of today's most influential researchers. This BBC Radio 4 podcast treats science not as a remote collection of facts, but as a deeply human endeavor driven by passion, perseverance, and sometimes, serendipity. The discussions delve into the real process of discovery-the late-night frustrations, the collaborative breakthroughs, and the ethical questions that arise from new knowledge. While exploring everything from the smallest particles to the vastness of the cosmos, the core of each episode remains the individual behind the science. Listeners come to understand not just what these scientists know, but who they are and what continues to drive them forward. It’s a series that connects the personal to the universal, making complex fields accessible and profoundly relevant. By focusing on the life as much as the science, this podcast reveals how our future is being built, one question at a time, in labs, field stations, and offices around the globe.
Author: Language: English Episodes: 100

The Life Scientific
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