The Longevity & Lifestyle Podcast
Why does hunger feel so loud — and why does willpower so often fail?
In this illuminating episode, Sarah Kennedy, founder and CEO of Calocurb, unpacks the biology of hunger, the gut-brain axis, and the powerful role of GLP-1 in appetite regulation. Drawing on over 15 years and $30 million of New Zealand government-backed science, Sarah explains why hunger is driven by our most primitive brain systems — and how understanding this biology can finally bring peace with food.
We explore how bitter taste receptors in the gut stimulate appetite-suppressing hormones, why dieting can actually increase hunger over time, and how natural GLP-1 activation differs fundamentally from pharmaceutical injections like Ozempic.
We explore:
This is a science-grounded, compassionate conversation that reframes hunger — not as a personal failure, but as biology you can finally work with.
This episode was brought to you by: