Special Episode: Brain Preservation and Abolishing Death

Special Episode: Brain Preservation and Abolishing Death

Author: James Fodor May 4, 2025 Duration: 1:16:05
An interview with Ariel Zeleznikow-Johnston, author of the book 'The Future Loves You: How and Why We Should Abolish Death'. We begin by discussing how best to define death, focusing on the idea of death as the permanent disruption of psychological identity, and how such identity is constituted by our personality, desires, and memories. We then consider the science of brain preservation, including the recently-developed technique of Aldehyde-Stabilized Cryopreservation, and how it could be used to indefinitely preserve the brain structure that encodes or personal identity. Ariel argues that such a preserved brain could potentially be used to construct a digital simulation of our brains, essentially allowing us to survive the biological death of our bodies. We conclude by considering some potential challenges of implementign such a technology, and whether it would achieve widespread social acceptance. Ariel's book: The Future Loves You: How and Why We Should Abolish Death Turning Fate into Choice: Patient Self-Determination and Life Extension More on brain preservation: A case for developing Aldehyde Stabilized Cryopreservation into a medical procedure How much protein structure loss is there following glutaraldehyde crosslinking? Large Mammal BPF Prize Winning Announcement Mapping the Drosophila brain: The connectome of an insect brain | Science      

Curiosity about how the world works is a universal trait, and The Science of Everything Podcast is built on that very impulse. Host James Fodor guides conversations that roam freely across disciplines, from the physics of black holes to the complexities of human behavior studied in social sciences. Each episode feels like a deep dive into a new subject, where the common thread is a rigorous yet accessible application of the scientific method. You’ll hear explanations that break down complex ideas without oversimplifying them, focusing on the fascinating insights that research reveals about our universe and our place within it. This isn't a lecture series, but rather an exploration driven by genuine inquiry. Whether the topic is rooted in biology, chemistry, sociology, or astronomy, the aim is to connect the dots between abstract principles and the tangible reality we experience. The result is a consistently engaging audio experience that reminds us just how much there is left to discover. Tune in to this thoughtful podcast for a regular dose of understanding, designed to satisfy both the casual question-asker and the dedicated lifelong learner.
Author: Language: English Episodes: 50

The Science of Everything Podcast
Podcast Episodes
Episode 154: Magnetic Resonance Imaging [not-audio_url] [/not-audio_url]

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An overview of Magnetic Resonance Imaging (MRI), beginning from the basic physics of nuclear magnetic resonance, and covering the use of radiowaves to excite nuclear spin states, and the T1 and T2 modes of relaxation. We…
Episode 153: Low Carb Diets [not-audio_url] [/not-audio_url]

Duration: 1:14:03
A review of the carbohydrate insulin model of obesity and the related proposal that low carbohydrate diets are superior to traditional low fat diets. I begin with a discussion of the theory behind the carbohydrate insuli…
Episode 152: Obesity, Diabetes, and Hypertension [not-audio_url] [/not-audio_url]

Duration: 1:16:34
A review of the science between the metabolic syndrome, including discussion of obesity, diabetes, hypertension, and hyperlipidemia. We discuss the pathophysiology of how enlargement of adipocytes disrupts metabolic sign…
Episode 151: Diet and Nutrition [not-audio_url] [/not-audio_url]

Duration: 1:14:45
An introduction to human nutrition, in which we discuss the nutritional importance and role of carbohydrates, fats, proteins, vitamins, and minerals, before considering the effects of malnutrition, how it is measured, an…
Episode 150: How Home Appliances Work [not-audio_url] [/not-audio_url]

Duration: 1:17:11
An exploration into the exciting world of home appliances and devices. We begin with a journey through the kitchen, discussing the design and operating principles behind the refrigerator, rice cooker, convection oven, mi…
Episode 149: The Psychology of Personality [not-audio_url] [/not-audio_url]

Duration: 44:58
An introduction to the psychological study of personality, beginning with a definition of what is and is not personality and a brief history of the development of the field from Freud and Jung through the Myers-Briggs In…
Episode 148: Control of Gene Expression [not-audio_url] [/not-audio_url]

Duration: 1:09:05
An introduction to the processes by which cells control which genes are expressed. We begin with an overview of why genetic regulation is necessary and the key stages where such regulation occurs, including key concepts…
Episode 147: Genetic Mutation and Repair [not-audio_url] [/not-audio_url]

Duration: 1:13:51
Here we survey of the causes and consequences of genetic mutation, including a discussion of mechanisms of endogenous and induced mutations, rates of mutation, types of single nucleotide mutations, and the phenotypic eff…
Episode 146: Mendelian Genetics and Inheritance [not-audio_url] [/not-audio_url]

Duration: 1:22:34
An introduction to classical Mendelian genetics, in which we discuss Mendel's experiments with peas and the laws of heredity that he discovered, including inheritance of one allele from each parent, the law of dominance,…
Episode 145: Relativity and Black Holes [not-audio_url] [/not-audio_url]

Duration: 1:25:43
Continuing our series on General Relativity, we discuss the derivation of the Schwarzschild metric as a vacuum solution to Einstein's Field Equations, and analyse the physical meaning of this solution, including the prop…