Special Episode: Brain Preservation and Abolishing Death

Special Episode: Brain Preservation and Abolishing Death

Author: James Fodor May 4, 2025 Duration: 1:16:05
An interview with Ariel Zeleznikow-Johnston, author of the book 'The Future Loves You: How and Why We Should Abolish Death'. We begin by discussing how best to define death, focusing on the idea of death as the permanent disruption of psychological identity, and how such identity is constituted by our personality, desires, and memories. We then consider the science of brain preservation, including the recently-developed technique of Aldehyde-Stabilized Cryopreservation, and how it could be used to indefinitely preserve the brain structure that encodes or personal identity. Ariel argues that such a preserved brain could potentially be used to construct a digital simulation of our brains, essentially allowing us to survive the biological death of our bodies. We conclude by considering some potential challenges of implementign such a technology, and whether it would achieve widespread social acceptance. Ariel's book: The Future Loves You: How and Why We Should Abolish Death Turning Fate into Choice: Patient Self-Determination and Life Extension More on brain preservation: A case for developing Aldehyde Stabilized Cryopreservation into a medical procedure How much protein structure loss is there following glutaraldehyde crosslinking? Large Mammal BPF Prize Winning Announcement Mapping the Drosophila brain: The connectome of an insect brain | Science      

Curiosity about how the world works is a universal trait, and The Science of Everything Podcast is built on that very impulse. Host James Fodor guides conversations that roam freely across disciplines, from the physics of black holes to the complexities of human behavior studied in social sciences. Each episode feels like a deep dive into a new subject, where the common thread is a rigorous yet accessible application of the scientific method. You’ll hear explanations that break down complex ideas without oversimplifying them, focusing on the fascinating insights that research reveals about our universe and our place within it. This isn't a lecture series, but rather an exploration driven by genuine inquiry. Whether the topic is rooted in biology, chemistry, sociology, or astronomy, the aim is to connect the dots between abstract principles and the tangible reality we experience. The result is a consistently engaging audio experience that reminds us just how much there is left to discover. Tune in to this thoughtful podcast for a regular dose of understanding, designed to satisfy both the casual question-asker and the dedicated lifelong learner.
Author: Language: English Episodes: 50

The Science of Everything Podcast
Podcast Episodes
Episode 127: Weathering, Erosion, and Rivers [not-audio_url] [/not-audio_url]

Duration: 1:04:37
The first in a new series on geomorphology, in which I review the main erosion processes that shape landforms of the natural environment. Here I discuss the key mechanisms of physical and chemical weathering, outline the…
Episode 126: Depression and Serotonin [not-audio_url] [/not-audio_url]

Duration: 45:53
An exploration of the role of the neurotransmitter serotonin in the development of depression. I discuss the role of serotonin in promoting the production of neurotrophic growth factor, the role the growth factor plays i…
Special Episode: Genetic Testing [not-audio_url] [/not-audio_url]

Duration: 52:56
In this special episode I discuss genetic testing with Kira Dineen from DNA Today. We cover a range of topics including the process and science behind genetic testing, the types of genetic conditions that can be tested f…
Episode 125: Earthquakes [not-audio_url] [/not-audio_url]

Duration: 1:07:05
A discussion of earthquakes, covering the elastic rebound theory of earthquake generation, the phenomena of deep and intraplate earthquakes, types of seismic waves, methods of earthquake detection, different ways in whic…
Episode 124: Volcanoes [not-audio_url] [/not-audio_url]

Duration: 55:29
A discussion of the awesome power of volcanoes, including an overview of the different types of volcanoes, types of lava and pyroclastics, mechanisms of volcanic eruptions, a curvey of volcanic landforms, and a review of…
Episode 123: Respiratory and Circulatory Systems Part 2 [not-audio_url] [/not-audio_url]

Duration: 1:00:28
Concluding the two-part series on the circulatory and respiratory systems, I discuss the biochemical mechanisms by which red blood cells and hemoglobin molecules deliver oxygen to the tissues and carbon dioxide to the lu…
Episode 122: Respiratory and Circulatory Systems Part 1 [not-audio_url] [/not-audio_url]

Duration: 47:54
The first in a two-part episode covering the circulatory and respiratory systems, including a discussion of the anatomy of the heart, the process of contraction, and the generation and propagation of electrical activity.…
Episode 121: The Biology of Pain [not-audio_url] [/not-audio_url]

Duration: 51:06
An overview of the underlying mechanisms of pain, including the role of nociception, transduction of nociceptor signals by spinal pathways, the modulatory effects of opioids, and processing of these inputs in the brain.…
Episode 120: Computational Chemistry Part 2 [not-audio_url] [/not-audio_url]

Duration: 1:13:01
Building on the previous discussion of Hartree-Fock Theory, I discuss the inclusion of basis functions to produce the Roothaan equations, and the method of solving these using self-consistent field methods. I then provid…