The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314

The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314

Author: Jason Calacanis July 20, 2026 Duration: 42:00
This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's show: *Cybersecurity has long focused on cleaning up a system AFTER a breach but Ent founder Brandon Dixon says that's backwards. He just raised a $100M seed round to put an AI agent on everyone's company laptops that catches the risky clicks, leaked files, or rogue agents BEFORE they wreck havoc. PLUS Clawra creator David Im return swith his new project, Sume's Avatar, a multi-model orchestration layer that generates 60-second UGC videos from a single prompt… and gets it right on the first try, rather than falling back on trial and error. Guests: Brandon Dixon on LinkedIn: https://www.linkedin.com/in/brandonsdixon/ Ent: ****https://ent.ai/ David Im on X: https://x.com/davidim Sume: https://www.sume.com/ Relevant Links: WSJ: "Cyber Security Startup Ent Raises $100 Million in Seed Funding": https://www.wsj.com/pro/cybersecurity/cyber-startup-ent-raises-100-million-in-seed-funding-a3e9b6c6 Microsoft Security Copilot: https://www.microsoft.com/en-us/security/business/ai-machine-learning/microsoft-security-copilot Engadget: "Meta 'pausing' employee tracking program…": https://www.engadget.com/2199458/meta-is-pausing-employee-tracking-program-after-it-let-the-whole-company-see-sensitive-data/ Seedance 2.0: https://seedance2.ai/ Timestamps: 0:00 Intro: Why AI + cybersecurity is the hot combo right now 2:29 How INT stops breaches before they happen 4:56 AI is giving non-technical employees dangerous new powers 10:26 Vanta - Compliance and security shouldn't be a deal-breaker for startups to win new business. Vanta makes it easy for companies to get a SOC 2 report fast. Get $1,000 off for a limited time at https://www.vanta.com/twist 13:54 Why on-device AI beats cloud-based security 20:08 Superhuman - Get AI that works where you work. Unlock your Superhuman potential at https://superhuman.com 25:18 INT's business model and go-to-market 30:26 YSecurity - The on-demand security team for startups. Need enterprise-grade security without hiring a $400k CISO? YSecurity gives you 40+ expert engineers, matched to exactly what you need, by the hour, with your first six hours completely free. Go to https://YSecurity.io/TWIST 34:18 David M. of Sumi Labs: one-shotting AI video 36:10 Live demo: Sumi's video orchestration API 40:05 Consistent faces, 60-second videos, and who's buying Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason's suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

Every week, Jason Calacanis dives headfirst into the swirling vortex of Silicon Valley and global tech with This Week in Startups. It’s a direct line to the conversations shaping our digital future, moving far beyond surface-level news. You’ll hear Jason’s unfiltered analysis on everything from market shifts and media trends to the underlying mechanics of building a business, all delivered with a blend of enthusiasm and seasoned skepticism. The core of this podcast, however, lies in the guests. Jason sits down with the very people driving change-founders who have scaled impossible heights, operators managing daily chaos, and investors who spot trends before they become obvious. These conversations are less like formal interviews and more like insider debriefs, pulling back the curtain on real strategies, painful failures, and unexpected successes. For anyone curious about how technology is built, funded, and ultimately changes the world, this series offers a front-row seat. It’s the context behind the headlines, providing a deeper understanding of the forces at play in startups and technology. Tune in for a consistently engaging and insightful look at the ecosystem, straight from someone who lives and breathes it.
Author: Language: en-us Episodes: 50

This Week in Startups
Podcast Episodes
The Startup Building the First Hotel on the Moon… [not-audio_url] [/not-audio_url]

Duration: 1:40:54
This Week In Startups is made possible by: Every.io - visit every.io Sentry.io - sentry.io/twist Vanta - vanta.com/twist Today's show: The next SpaceX won't be building rockets; it'll build the first hotel on the Moon. T…
SpaceX IPO Day: What Wall St. and the media missed | E2300 [not-audio_url] [/not-audio_url]

Duration: 1:19:56
This Week In Startups is made possible by: Plaud https://Plaud.ai/twist Pilot https://pilot.com/twist Agree https://agree.com IM8 Health https://IM8health.com/twist After watching Elon build out his rocket (and AI) compa…
Why the most expensive Seed deals are the cheapest | E2299 [not-audio_url] [/not-audio_url]

Duration: 1:08:23
This Week In Startups is made possible by: NetSuite - Netsuite.com/TWiST Deel - Deel.com/TWiST Squarespace - Squarespace.com/TWiST Two days before SpaceX launches the largest IPO in history at a flat $135/share, our VC r…
The AI Tutor That Makes Kids Actually Think | E2298 [not-audio_url] [/not-audio_url]

Duration: 1:00:19
The AI Tutor That Makes Kids Actually Think | E2298 This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist LinkedIn Jobs https://LinkedIn.com/twist Shopify https:…
The project SpaceX's first employee raised $500M for [not-audio_url] [/not-audio_url]

Duration: 1:01:36
This Week In Startups is made possible by: Northwest Registered Agent - NorthwestRegistereAagent.com/TWIST Every - Every.io Sentry - Sentry.io/TWIST Today's show: Want to get to space? Several launch companies can help y…
This Startup Fused Human Brain Cells with Silicon Chips | E2295 [not-audio_url] [/not-audio_url]

Duration: 1:06:16
This Week In Startups is made possible by: Deel https://deel.com/twist Quo https://quo.com/TWiST LinkedIn Jobs https://LinkedIn.com/twist Today's show: Cortical Labs is the world's first company selling biological comput…
How to Raise a Seed Round in 2026: Ask Jason | E2294 [not-audio_url] [/not-audio_url]

Duration: 57:55
This Week In Startups is made possible by: Grasshopper Bank https://grasshopper.bank/twistLinkedIn Jobs https://LinkedIn.com/twistNorthwest Registered Agent https://northwestregisteredagent.com/twist Today's show: Jason…
The Drone Company Quietly Taking Over Delivery [not-audio_url] [/not-audio_url]

Duration: 1:01:23
This Week In Startups is made possible by: Render - render.com/twist Deel - deel.com/twist Northwest Registered Agent - northwestregisteredagent.com/twist Today's show: The "Ryanair of drone delivery" just raised $50 mil…