How Understanding Your Brain Chemistry Can Change Your Life

How Understanding Your Brain Chemistry Can Change Your Life

Author: Zak Rosen April 22, 2026 Duration: 20:28
Mike Pesca is the creator and host of The Gist, the longest-running daily news podcast in history, moderator of Not Even Mad, a political debate podcast, and host of Funny You Should Mention, a co-production with the Comedy Cellar, where he conducts in-depth interviews with stand up comedians. On today's show we get into how understanding your own neurochemistry can offer new perspectives on mental health and anxiety. READ: Opinion | The Feel-Good Gene LISTEN: How to address acute anxiety with Terry Rawls --- LISTEN: You in Mind |Yoni London --- LISTEN TO WH ad-free by becoming a Patron today! WH MERCH IS HERE!!!!!!!! Learn more about your ad choices. Visit megaphone.fm/adchoices

Hosted by Zak Rosen, Weirdly Helpful (which you might remember as The Best Advice Show) operates on a simple, charming premise: the most effective strategies for getting through the day aren't always the most obvious ones. This is a weekly, compact podcast built on the idea that a slight shift in perspective or a deliberately odd action can recalibrate your mood or solve a stubborn problem. Each episode features a different guest contributor sharing one specific, curious tactic they personally use. You won't get lengthy lectures or clinical self-help here. Instead, you'll hear about tangible, often playful experiments and rituals-think of it as a friendly, audio-based swap meet for life hacks that are delightfully left of center. The practices discussed are genuinely unconventional, yet presented with such warmth and clarity that their utility becomes undeniable. It’s that moment of surprised recognition when something seemingly bizarre, like vocalizing frustration in a primal way or transforming a daily routine into a small sensory celebration, clicks into place as profoundly sensible. The podcast lives in the intersection of Education, Fitness, and Mental Health precisely because improving daily life touches all those facets. Rosen curates these conversations to be short bursts of inspiration, leaving you with a single, actionable idea to sit with and perhaps try for yourself, wondering why you hadn't thought of it before. The cumulative effect of listening is a gentle expansion of what you consider helpful, finding value and a bit of magic in the wonderfully strange.
Author: Language: English Episodes: 50

Weirdly Helpful (formerly The Best Advice Show)
Podcast Episodes
This is How to Aura Farm Without Being Overly Cringe [not-audio_url] [/not-audio_url]

Duration: 14:03
Natalie and Jacob are sibling youths from Texas. --- SUPPORT WEIRDLY HELPFUL and listen to the show without ads by becoming a Patron today @ https://www.patreon.com/weirdlyhelpful Learn more about your ad choices. Visit…
Stop Feeling Guilty About Your Guilty Pleasures with Fabiola Lara [not-audio_url] [/not-audio_url]

Duration: 10:15
Fabiola Lara is a Chilean-born, Florida-raised artist! She lives in flux of feeling simultaneously too American to be Chilean and too Chilean to be American, and is constantly navigating her identity as a white Latinx an…
How Much Capacity Do You Have Today? with Bridget Thoreson [not-audio_url] [/not-audio_url]

Duration: 13:29
Bridget Thoreson is an award-winning journalist, executive, and creator of the Career River framework. Check out her Weirdly Helpful episode about floating down the career river. --- Listen to WH ad-free by becoming a Pa…
"Hey Buddy!" Let's Talk About Why You Feel Doomed with Andy J. Pizza [not-audio_url] [/not-audio_url]

Duration: 11:22
Andy J. Pizza is a New York Times Bestselling author-illustrator of many books for children and adults such as "Invisible Things" and "A Pizza with Everything On It". Pizza is also the creator of the popular podcast Crea…
Resolutions Smesolutions! Ta Ta 2025. [not-audio_url] [/not-audio_url]

Duration: 22:26
Happiest and healthiest of New Years to you and yours! Thank you for listening. Love, z ⁠SUPPORT WEIRDLY HELPFUL BY BECOMING A PATRON RIGHT NOW. Todays episode features morsels from the following Weirdly Helpers... Compa…