#222 – Can we tell if an AI is loyal by reading its mind? DeepMind's Neel Nanda (part 1)

#222 – Can we tell if an AI is loyal by reading its mind? DeepMind's Neel Nanda (part 1)

Author: The 80,000 Hours team September 8, 2025 Duration: 3:02:48

We don’t know how AIs think or why they do what they do. Or at least, we don’t know much. That fact is only becoming more troubling as AIs grow more capable and appear on track to wield enormous cultural influence, directly advise on major government decisions, and even operate military equipment autonomously. We simply can’t tell what models, if any, should be trusted with such authority.

Neel Nanda of Google DeepMind is one of the founding figures of the field of machine learning trying to fix this situation — mechanistic interpretability (or “mech interp”). The project has generated enormous hype, exploding from a handful of researchers five years ago to hundreds today — all working to make sense of the jumble of tens of thousands of numbers that frontier AIs use to process information and decide what to say or do.

Neel now has a warning for us: the most ambitious vision of mech interp he once dreamed of is probably dead. He doesn’t see a path to deeply and reliably understanding what AIs are thinking. The technical and practical barriers are simply too great to get us there in time, before competitive pressures push us to deploy human-level or superhuman AIs. Indeed, Neel argues no one approach will guarantee alignment, and our only choice is the “Swiss cheese” model of accident protection, layering multiple safeguards on top of one another.

But while mech interp won’t be a silver bullet for AI safety, it has nevertheless had some major successes and will be one of the best tools in our arsenal.

For instance: by inspecting the neural activations in the middle of an AI’s thoughts, we can pick up many of the concepts the model is thinking about — from the Golden Gate Bridge, to refusing to answer a question, to the option of deceiving the user. While we can’t know all the thoughts a model is having all the time, picking up 90% of the concepts it is using 90% of the time should help us muddle through — so long as mech interp is paired with other techniques to fill in the gaps.

In today’s episode, Neel takes us on a tour of everything you’ll want to know about this race to understand what AIs are really thinking. He and host Rob Wiblin cover:

  • The best tools we’ve come up with so far, and where mech interp has failed
  • Why the best techniques have to be fast and cheap
  • The fundamental reasons we can’t reliably know what AIs are thinking, despite having perfect access to their internals
  • What we can and can’t learn by reading models’ ‘chains of thought’
  • Whether models will be able to trick us when they realise they’re being tested
  • The best protections to add on top of mech interp
  • Why he thinks the hottest technique in the field (SAEs) are overrated
  • His new research philosophy
  • How to break into mech interp and get a job — including applying to be a MATS scholar with Neel as your mentor (applications close September 12!)

Learn more and read the full transcript on the 80,000 Hours website. 


This episode was recorded on July 17 and 21, 2025.

Part 2 of the conversation is now available! https://80k.info/nn2

What did you think? https://forms.gle/xKyUrGyYpYenp8N4A

Chapters:
• Cold open (00:00:00)
• Who’s Neel Nanda? (00:01:04)
• How would mechanistic interpretability help with AGI (00:02:01)
• What's mech interp? (00:05:12)
• How Neel changed his take on mech interp (00:09:50)
• Top successes in interpretability (00:16:00)
• Probes can cheaply detect harmful intentions in AIs (00:20:13)
• In some ways we understand AIs better than human minds (00:26:58)
• Mech interp won't solve all our AI alignment problems (00:29:30)
• Why mech interp is the 'biology' of neural networks (00:38:17)
• Interpretability can't reliably find deceptive AI — nothing can (00:40:38)
• 'Black box' interpretability: reading the chain of thought (00:49:51)
• 'Self-preservation' isn't always what it seems (00:53:17)
• For how long can we trust the chain of thought? (01:02:25)
• We could accidentally destroy chain of thought's usefulness (01:11:58)
• Models can tell when they’re being tested and act differently (01:17:14)
• Top complaints about mech interp (01:24:11)
• Why everyone's excited about sparse autoencoders (SAEs) (01:38:24)
• Limitations of SAEs (01:47:55)
• SAEs’ performance on real-world tasks (01:55:38)
• Best arguments in favour of mech interp (02:09:15)
• Lessons from the hype around mech interp (02:13:11)
• Where mech interp will shine in coming years (02:18:58)
• Why focus on understanding over control? (02:22:12)
• If AI models are conscious, will mech interp help us figure it out? (02:25:19)
• Neel’s new research philosophy (02:27:29)
• Who should join the mech interp field (02:39:42)
• Advice for getting started in mech interp (02:48:10)
• Keeping up to date with mech interp results (02:56:02)
• Who’s hiring? (02:59:06)

Host: Rob Wiblin
Video editing: Simon Monsour, Luke Monsour, Dominic Armstrong, and Milo McGuire
Audio engineering: Ben Cordell, Milo McGuire...


The 80,000 Hours Podcast, from The 80,000 Hours team, digs into the complex and often overlooked questions surrounding how we can best use our careers to tackle the world's most pressing problems. While artificial intelligence is a recurring and critical theme, framing some of the most important conversations you won't hear elsewhere, the discussions range far wider into the intersections of technology, policy, philosophy, and global priorities. Hosts Rob Wiblin, Luisa Rodriguez, and Zershaaneh Qureshi guide in-depth interviews with researchers, policymakers, and practitioners, breaking down daunting ideas into actionable insights. You'll hear nuanced analyses of career paths, ethical dilemmas in emerging tech, and evidence-based strategies for creating a positive impact. This isn't about quick tips; it's about deep, substantive exploration of how specific choices and systemic changes can lead to a better future. The podcast lives in the Education and Technology categories because it fundamentally aims to equip listeners with the knowledge and perspective to navigate a rapidly changing world thoughtfully. Each episode is built on rigorous research, challenging assumptions while maintaining a conversational and accessible tone. Tune in for a consistently engaging and intellectually honest look at the forces shaping our century and the practical steps individuals can take within their own 80,000-hour working lives to make a meaningful difference.
Author: Language: English Episodes: 50

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