Donnie Yance: Why Microdosing is More Effective Than Macrodosing

Donnie Yance: Why Microdosing is More Effective Than Macrodosing

Author: Abel James December 4, 2025 Duration: 1:15:31
Is microdosing more effective than macrodosing?

While heavy-handed megadoses of synthetic pharmaceuticals attempt to dominate a single biochemical pathway, microdoses of synergistic botanticals can stimulate the body to normalize, balance and heal itself.

Meanwhile, much of modern medicine has devolved into a game of manipulating numbers on blood tests rather than actually healing you.

Because they're not so easily patented and monetized, many of the most effective, affordable and simple substances and practices in health and longevity are dismissed, ignored, or at the very least taken for granted.

For instance, did you know that the simple act of prayer has been scientifically proven to not only improve mental health, but also improve the literal physical health of the heart?

Deep breathing, gratitude, meditation, and prayer steady the vagus nerve and allow our bodies to remain flexible and adaptable, downregulating our nervous system from fight-or-flight into a relaxed parasympathetic state.

The truth is, we don't need to wait for the next miracle pill to save us. We already know more than enough to put life-saving practices into action today.

Donnie Yance is a Clinical Master Herbalist, Certified Nutritionist and Author, known internationally for his pioneering work in botanical and nutritional medicine, particularly in the field of integrative cancer. As an accomplished jazz bassist and former monk, Donnie is also known as "The Funk Monk."

In this episode, you'll discover:
  • How to eat and supplement for greater adaptive capacity, hardiness, and resilience
  • Why many of the secrets to long life lie in humble living
  • How Donnie earned the nickname of "The Funk Monk"
  • How improvisation in music mirrors the intellectual and playful flexibility we need in health
  • And much more...
Find Donnie Yance and his work at: 
Books by Donnie Yance: 
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For over a decade, the Abel James Show has served as a deep and often surprising conversation space where health, business, and human potential intersect. Rather than offering quick fixes, this podcast delves into the nuanced strategies and personal philosophies of top performers across diverse fields. You’ll hear candid, long-form interviews with hundreds of pioneers, from biochemists like Dr. Casey Means and longevity experts like Dr. Mark Hyman to entrepreneurial minds such as Tim Ferriss and James Clear. The discussions naturally explore the practical connections between metabolic health, cognitive performance, and building a meaningful career or business. Launched back in 2012, the show has evolved from its original, playful focus into a broader exploration of what it means to live well and work smart. Tuning in provides a unique blend of actionable science for your body and innovative thinking for your ventures, all framed through Abel’s engaging and curious perspective. Each episode feels like a chance to sit in on a private masterclass, stripping away the hype to examine what truly works for optimizing a modern life.
Author: Language: English Episodes: 100

Abel James Show
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