Inflammation: The Hidden Fire Behind Pain, Aging, and Disease

Inflammation: The Hidden Fire Behind Pain, Aging, and Disease

Author: Dr. Mark Hyman October 20, 2025 Duration: 1:20:35
A hidden fire called chronic inflammation drives many problems—from joint pain and arthritis to autoimmune conditions, and even faster aging. Typical fixes (like pain meds and steroid shots) calm symptoms but often miss the “why,” and can leave people still hurting or even create more issues. Big triggers of inflammation that impact our joints, and so much more, include sugar and refined carbs, extra weight, leaky gut, toxins, infections, stress, and poor sleep—plus joints naturally get less blood and oxygen as we age. This is why it’s important to create an anti-inflammatory lifestyle plan starting with real whole foods, and incorporating regular exercise, stress management, gut repair, and targeted anti-inflammatory supplements.  In this episode, I discuss, along with Dr. George Papanicolaou and Dr. Cindy Geyer, how chronic inflammation, arthritis, and joint pain can be reduced using a Functional Medicine approach, including how to do the anti-inflammatory 10-Day Detox diet.  Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is Board Certified in Family Medicine from Abington Memorial Hospital. Over time as the healthcare system made it harder for patients to receive personal care, Dr. Papanicolaou decided a change was needed. He began training in Functional Medicine through the Institute of Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. In August 2017, Dr. Papanicolaou joined The UltraWellness Center. Dr. Cindy Geyer received her bachelor of science and her doctor of medicine degrees, with honors, from the Ohio State University. She completed residency in internal medicine at Strong Memorial Hospital in Rochester, N.Y. and is triple board certified in internal medicine, integrative medicine and lifestyle medicine. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here: Prolozone and Nutritional Therapy for Osteoarthritis What Causes Inflammation And How Can You Treat It? Is An Autoimmune Condition Driving Your Raynaud's Syndrome? How To Do The 10-Day Detox

Hosted by physician and functional medicine pioneer Dr. Mark Hyman, The Dr. Hyman Show is a conversation about reclaiming your well-being. Each episode digs into the interconnected systems that shape our health, moving beyond symptom management to address foundational causes. You’ll hear detailed discussions on nutrition, the roots of chronic disease, mental health strategies, and the science of longevity, all framed through a functional medicine lens. Dr. Hyman engages with leading experts and thinkers to challenge conventional wisdom on food policy and prevention, offering a practical and often provocative perspective. This podcast serves as a resource for anyone feeling lost in a healthcare system that can overlook root causes, providing actionable knowledge to make informed daily choices. Tune in for a deep, evidence-based exploration of how our bodies truly work, empowering you to reimagine your personal health potential through informed dialogue and discovery.
Author: Language: English Episodes: 100

The Dr. Hyman Show
Podcast Episodes
Why Your Cholesterol Is High—and How to Start Fixing It in 10 Days [not-audio_url] [/not-audio_url]

Duration: 23:46
High cholesterol is one of the most common reasons people are told they’re at risk for heart disease. But what if cholesterol isn’t the root problem? What if it’s actually a signal of deeper metabolic dysfunction—and foc…
Are You Secretly Dehydrated? Why a 1% Drop Kills Your Focus and Mood [not-audio_url] [/not-audio_url]

Duration: 18:32
Hydration affects far more than thirst. Even mild dehydration can impact your focus, memory, mood, energy, and overall brain performance—yet most people walk through the day without realizing they’re under-hydrated. The…
The 5 Root Causes of Autoimmune Disease (And How to Start Healing) [not-audio_url] [/not-audio_url]

Duration: 27:08
Autoimmune disease is often treated as something random, lifelong, and out of your control. But what if it’s not your body malfunctioning—what if it’s your immune system responding exactly the way it’s designed to, to so…
The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin [not-audio_url] [/not-audio_url]

Duration: 1:12:53
We tend to think of heart disease, cancer, and Alzheimer’s as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose r…