Millions of Women Stopped Taking Hormones Because of a Misread Study | Dr. Sharon Malone

Millions of Women Stopped Taking Hormones Because of a Misread Study | Dr. Sharon Malone

Author: Dr. Mark Hyman May 27, 2026 Duration: 1:27:37
For far too long, many women have been told their symptoms were normal, exaggerated, or simply something they had to live with—treated as isolated problems instead of part of a much larger hormonal transition happening inside the body. On this episode of The Dr. Hyman Show, I’m joined by Dr. Sharon Malone, host of The Second Opinion podcast and Chief Medical Advisor at Alloy Women’s Health. We discuss how menopause and hormone therapy became so misunderstood, the real story behind the Women’s Health Initiative study, and why a more individualized, prevention-focused approach to women’s health is long overdue. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We explore: Why so many women enter perimenopause completely unprepared—and how symptoms can begin years before menopause officially starts What the Women’s Health Initiative actually found, and how one medical narrative reshaped women’s healthcare for decades How menopause affects far more than reproduction, including the brain, heart, sleep, metabolism, and bone health What you should know about hormone therapy today, including timing, individualized treatment, and understanding risk in context The daily habits that still matter most for healthy aging, whether or not you choose hormone therapy Midlife health should never be reduced to “just deal with it.” The more women understand what’s happening inside their bodies, the earlier they can take steps to protect their long-term health and quality of life. View Show Notes From This Episode Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - ⁠Click Here⁠ Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Paleovalley, Pique, Perfect Amino, Rho, Sunlighten and BIOptimizers. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. (0:00) Introduction, survey on hormone use, and Dr. Sharon Malone’s expertise   (4:04) Importance of women's health research and historical neglect   (5:35) Lack of education and preparation for menopause   (6:28) Societal and historical biases in women's health   (9:05) Observational studies vs. randomized controlled trials   (13:30) Life cycles, hormonal changes, and stages in women   (19:26) Detailed stages of hormonal changes and perimenopause   (23:00) Misdiagnosis and definition of menopause   (25:02) The term "postmenopausal" and its significance   (26:34) Impact of menopause on organ systems and major symptoms   (31:19) Lifestyle factors and hormone therapy options   (39:25) Black box warning, Women’s Health Initiative, and therapy timing   (45:00) Women's Health Initiative findings and breast cancer risk   (47:57) Reinterpreting breast cancer risk and black box warning   (53:21) Personalized hormone therapy and clinical diagnosis   (59:55) Importance of estrogen and bioidentical vs. synthetic hormones   (1:03:35) Addressing sexual health and testosterone use for women   (1:08:05) FDA-approved peptides for women’s arousal disorder   (1:09:57) Long-term benefits of hormone therapy   (1:12:43) Early menopause, hormone therapy, and health impacts   (1:15:07) Estrogen’s role in brain health and dementia prevention   (1:16:22) Alzheimer’s risk in women and hormonal 

Hosted by physician and functional medicine pioneer Dr. Mark Hyman, The Dr. Hyman Show is a conversation about reclaiming your well-being. Each episode digs into the interconnected systems that shape our health, moving beyond symptom management to address foundational causes. You’ll hear detailed discussions on nutrition, the roots of chronic disease, mental health strategies, and the science of longevity, all framed through a functional medicine lens. Dr. Hyman engages with leading experts and thinkers to challenge conventional wisdom on food policy and prevention, offering a practical and often provocative perspective. This podcast serves as a resource for anyone feeling lost in a healthcare system that can overlook root causes, providing actionable knowledge to make informed daily choices. Tune in for a deep, evidence-based exploration of how our bodies truly work, empowering you to reimagine your personal health potential through informed dialogue and discovery.
Author: Language: English Episodes: 100

The Dr. Hyman Show
Podcast Episodes
The Biohacks Ben Greenfield No Longer Uses (and What He Does Instead) [not-audio_url] [/not-audio_url]

Duration: 1:25:26
It’s been five years since Ben Greenfield joined me on The Dr. Hyman Show, and a lot has changed. Ben isn’t doing many of the things he once swore by. In fact, he’s discovered that some of the most powerful practices for…
Beyond Hot Flashes: Thriving Through Menopause into Your Best Years [not-audio_url] [/not-audio_url]

Duration: 55:43
As women enter perimenopause and menopause, hormonal shifts—declining estrogen, progesterone, and testosterone—can ripple through nearly every system in the body, impacting bone density, cardiovascular health, metabolism…
Why Whole Foods Founder John Mackey Is Tackling America’s Health [not-audio_url] [/not-audio_url]

Duration: 1:03:44
In a world where healthcare often focuses on treating illness rather than promoting wellness, what does it really take to live a healthy, vibrant life? In this episode of The Dr. Hyman Show, I sit down with John Mackey,…
How Relationships Heal Inflammation, Trauma, and Your Nervous System [not-audio_url] [/not-audio_url]

Duration: 1:07:08
Relationships have the power to change lives in ways both visible and hidden. Deep, supportive bonds can quiet inflammation in the body, protect against disease, and anchor people through decades of triumphs and trials.…
Bonus Episode: Reversing Fatty Liver at the UltraWellness Center [not-audio_url] [/not-audio_url]

Duration: 39:12
This special bonus episode features Dr. Todd LePine from the UltraWellness Center, diving into how functional medicine can help reverse fatty liver disease—an often-overlooked condition that’s quietly affecting millions.…
Scrolling Ourselves Sick: The Hidden Cost of Constant Connection [not-audio_url] [/not-audio_url]

Duration: 1:05:39
Social media platforms are designed to hijack our brain’s reward system, keeping us hooked through endless dopamine hits. This constant stimulation fragments our attention, reshapes our behavior, and can lead to burnout,…
Is Bipolar Disorder Really a Diet Problem w/ Dr. Iain Campbell [not-audio_url] [/not-audio_url]

Duration: 1:29:58
On this episode of The Dr. Hyman Show, we’re exploring the emerging science of metabolic psychiatry. My guest, Dr. Iain Campbell, is a researcher at the University of Edinburgh and someone who has lived with bipolar diso…