David Pfau: Manifold Factorization and AI for Science

David Pfau: Manifold Factorization and AI for Science

Author: Daniel Bashir July 11, 2024 Duration: 2:00:52

Episode 130

I spoke with David Pfau about:

* Spectral learning and ML

* Learning to disentangle manifolds and (projective) representation theory

* Deep learning for computational quantum mechanics

* Picking and pursuing research problems and directions

David’s work is really (times k for some very large value of k) interesting—I’ve been inspired to descend a number of rabbit holes because of it.

(if you listen to this episode, you might become as cool as this guy)

While I’m at it — I’m still hovering around 40 ratings on Apple Podcasts. It’d mean a lot if you’d consider helping me bump that up!

Enjoy—and let me know what you think!

David is a staff research scientist at Google DeepMind. He is also a visiting professor at Imperial College London in the Department of Physics, where he supervises work on applications of deep learning to computational quantum mechanics. His research interests span artificial intelligence, machine learning and scientific computing.

Find me on Twitter for updates on new episodes, and reach me at editor@thegradient.pub for feedback, ideas, guest suggestions.

I spend a lot of time on this podcast—if you like my work, you can support me on Patreon :) You can also support upkeep for the full Gradient team/project through a paid subscription on Substack!

Subscribe to The Gradient Podcast:  Apple Podcasts  | Spotify | Pocket Casts | RSSFollow The Gradient on Twitter

Outline:

* (00:00) Intro

* (00:52) David Pfau the “critic”

* (02:05) Scientific applications of deep learning — David’s interests

* (04:57) Brain / neural network analogies

* (09:40) Modern ML systems and theories of the brain

* (14:19) Desirable properties of theories

* (18:07) Spectral Inference Networks

* (19:15) Connections to FermiNet / computational physics, a series of papers

* (33:52) Deep slow feature analysis — interpretability and findings on eigenfunctions

* (39:07) Following up on eigenfunctions (there are indeed only so many hours in a day; I have been asking the Substack people if they can ship 40-hour days, but I don’t think they’ve gotten to it yet)

* (42:17) Power iteration and intuitions

* (45:23) Projective representation theory

* (46:00) ???

* (46:54) Geomancer and learning to decompose a manifold from data

* (47:45) we consider the question of whether you will spend 90 more minutes of this podcast episode (there are not 90 more minutes left in this podcast episode, but there could have been)

* (1:08:47) Learning embeddings

* (1:11:12) The “unexpected emergent property” of Geomancer

* (1:14:43) Learned embeddings and disentangling and preservation of topology

* n/b I still haven’t managed to do this in colab because I keep crashing my instance when I use s3o4d :(

* (1:21:07) What’s missing from the ~ current (deep learning) paradigm ~

* (1:29:04) LLMs as swiss-army knives

* (1:32:05) RL and human learning — TD learning in the brain

* (1:37:43) Models that cover the Pareto Front (image below)

* (1:46:54) AI accelerators and doubling down on transformers

* (1:48:27) On Slow Research — chasing big questions and what makes problems attractive

* (1:53:50) Future work on Geomancer

* (1:55:35) Finding balance in pursuing interesting and lucrative work

* (2:00:40) Outro

Links:

* Papers

* Natural Quantum Monte Carlo Computation of Excited States (2023)

* Making sense of raw input (2021)

* Integrable Nonparametric Flows (2020)

* Disentangling by Subspace Diffusion (2020)

* Ab initio solution of the many-electron Schrödinger equation with deep neural networks (2020)

* Spectral Inference Networks (2018)

* Connecting GANs and Actor-Critic Methods (2016)

* Learning Structure in Time Series for Neuroscience and Beyond (2015, dissertation)

* Robust learning of low-dimensional dynamics from large neural ensembles (2013)

* Probabilistic Deterministic Infinite Automata (2010)

* Other

* On Slow Research

* “I just want to put this out here so that no one ever says ‘we can just get around the data limitations of LLMs with self-play’ ever again.”



Get full access to The Gradient at thegradientpub.substack.com/subscribe

Hosted by Daniel Bashir, The Gradient: Perspectives on AI moves beyond surface-level headlines to explore the intricate machinery and human ideas shaping artificial intelligence. Each episode is built on a foundation of deep research, leading to conversations that are both technically substantive and broadly accessible. You'll hear from researchers, engineers, and philosophers who are actively building and critiquing our technological future, discussing not just how AI systems work, but the larger implications of their integration into society. This isn't about speculative hype; it's a grounded examination of real progress, persistent challenges, and ethical considerations from those on the front lines. The discussions peel back layers on topics like model architecture, policy, and the fundamental science behind the algorithms becoming part of our daily lives. For anyone curious about the substance behind the buzz-whether you have a technical background or are simply keen to understand a defining technology of our age-this podcast offers a crucial and thoughtful resource. Tune in for a consistently detailed and nuanced take that treats artificial intelligence with the complexity it deserves.
Author: Language: English Episodes: 100

The Gradient: Perspectives on AI
Podcast Episodes
Daniel Situnayake: AI on the Edge [not-audio_url] [/not-audio_url]

Duration: 1:58:07
In episode 67 of The Gradient Podcast, Daniel Bashir speaks to Daniel Situnayake. Daniel is head of Machine Learning at Edge Impulse. He is co-author of the O’Reilly books "AI at the Edge" and "TinyML". Previously, he’s…
Soumith Chintala: PyTorch [not-audio_url] [/not-audio_url]

Duration: 1:08:20
In episode 66 of The Gradient Podcast, Daniel Bashir speaks to Soumith Chintala.Soumith is a Research Engineer at Meta AI Research in NYC. He is the co-creator and lead of Pytorch, and maintains a number of other open-so…
Sewon Min: The Science of Natural Language [not-audio_url] [/not-audio_url]

Duration: 1:42:44
In episode 65 of The Gradient Podcast, Daniel Bashir speaks to Sewon Min.Sewon is a fifth-year PhD student in the NLP group at the University of Washington, advised by Hannaneh Hajishirzi and Luke Zettlemoyer. She is a p…
Richard Socher: Re-Imagining Search [not-audio_url] [/not-audio_url]

Duration: 1:37:49
In episode 64 of The Gradient Podcast, Daniel Bashir speaks to Richard Socher.Richard is founder and CEO of you.com, a new search engine that lets you personalize your search workflow and eschews tracking and invasive ad…
Joe Edelman: Meaning-Aligned AI [not-audio_url] [/not-audio_url]

Duration: 1:06:23
In episode 63 of The Gradient Podcast, Daniel Bashir speaks to Joe Edelman.Joe developed the meaning-based organizational metrics at Couchsurfing.com, then co-founded the Center for Humane Technology with Tristan Harris,…
Ed Grefenstette: Language, Semantics, Cohere [not-audio_url] [/not-audio_url]

Duration: 1:14:16
In episode 62 of The Gradient Podcast, Daniel Bashir speaks to Ed Grefenstette.Ed is Head of Machine Learning at Cohere and an Honorary Professor at University College London. He previously held research scientist positi…
Ken Liu: What Science Fiction Can Teach Us [not-audio_url] [/not-audio_url]

Duration: 2:02:40
In episode 61 of The Gradient Podcast, Daniel Bashir speaks to Ken Liu.Ken is an author of speculative fiction. A winner of the Nebula, Hugo, and World Fantasy awards, he is the author of silkpunk epic fantasy series Dan…
Hattie Zhou: Lottery Tickets and Algorithmic Reasoning in LLMs [not-audio_url] [/not-audio_url]

Duration: 1:42:59
In episode 60 of The Gradient Podcast, Daniel Bashir speaks to Hattie Zhou.Hattie is a PhD student at the Université de Montréal and Mila. Her research focuses on understanding how and why neural networks work, based on…
Steve Miller: Will AI Take Your Job? It's Not So Simple. [not-audio_url] [/not-audio_url]

Duration: 1:10:25
In episode 58 of The Gradient Podcast, Daniel Bashir speaks to Professor Steve Miller.Steve is a Professor Emeritus of Information Systems at Singapore Management University. Steve served as Founding Dean for the SMU Sch…