Label-free AI-enabled Imaging Flow Cytometry for Discovery of Subpopulations of Extravillous Trophoblast from a Stem Cell-based Model of Trophoblast Differentiation

Label-free AI-enabled Imaging Flow Cytometry for Discovery of Subpopulations of Extravillous Trophoblast from a Stem Cell-based Model of Trophoblast Differentiation

Author: UCTV August 22, 2026 Duration: 32:21
AI-powered cell imaging may help researchers identify biological differences that are difficult or impossible to see by eye. Yu-Hwa Lo, Ph.D., and Louise Laurent, M.D., Ph.D., describe a system that combines high-speed imaging, cell sorting, microfluidics, and artificial intelligence. The technology creates label-free images of cells, uses AI to classify them, and can isolate selected cells for deeper molecular analysis. Laurent explains how the team is applying the system to human trophoblast stem cells, which give rise to specialized placental cells involved in nutrient transport, hormone production, blood vessel remodeling, and immune regulation. Lo describes how AI can distinguish cell populations and identify features that may not be apparent to human observers. The researchers ultimately hope to connect imaging features with gene expression, proteins, and metabolism, allowing cell characteristics and behavior to be predicted from images alone. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41637]

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Author: Language: en-us Episodes: 50

University of California Video Podcasts (Video)
Podcast Episodes
The Moment of Decision [not-audio_url] [/not-audio_url]

Duration: 1:51:39
What is a decision, and why does decision-making matter in politics, history, war, and public life? This panel examines how decisions differ from choices, when decisions become political, and how theories of rational cho…
The Decision in History [not-audio_url] [/not-audio_url]

Duration: 1:59:39
Decision-making in history affects how societies understand power, responsibility, and change. Sir Christopher Clark, Regius Professor of History at the University of Cambridge, explains how narratives turn moments of de…
What is a Decision? [not-audio_url] [/not-audio_url]

Duration: 1:55:28
Political decision-making affects governments and societies in important ways. Sir Christopher Clark, Regius Professor of History at the University of Cambridge, explains how choices become decisions within political, le…
Menopause and Healthy Aging [not-audio_url] [/not-audio_url]

Duration: 1:16:55
Menopause and healthy aging affect women’s health and well-being in important ways. Dr. Tami Rowen explains how the best available evidence shapes menopausal management, with a focus on the data and safety around hormone…
Janelle Iglesias on Art Identity and Collaboration [not-audio_url] [/not-audio_url]

Duration: 51:15
Art can connect personal history, community, and social change. Janelle Iglesias, Assistant Professor of Studio Art at UC San Diego, traces her path from a multicultural childhood in Queens to anthropology, ceramics, scu…
Returning to the Moon [not-audio_url] [/not-audio_url]

Duration: 45:55
With the success of Artemis II, NASA is preparing for humanity’s return to the Moon through the ambitious Artemis Project. In this lecture, Professor Neil Farber explores the future Artemis missions, the spacecraft and t…