Label-free AI-enabled Imaging Flow Cytometry for Discovery of Subpopulations of Extravillous Trophoblast from a Stem Cell-based Model of Trophoblast Differentiation

Label-free AI-enabled Imaging Flow Cytometry for Discovery of Subpopulations of Extravillous Trophoblast from a Stem Cell-based Model of Trophoblast Differentiation

Author: UCTV August 22, 2026 Duration: 32:21
AI-powered cell imaging may help researchers identify biological differences that are difficult or impossible to see by eye. Yu-Hwa Lo, Ph.D., and Louise Laurent, M.D., Ph.D., describe a system that combines high-speed imaging, cell sorting, microfluidics, and artificial intelligence. The technology creates label-free images of cells, uses AI to classify them, and can isolate selected cells for deeper molecular analysis. Laurent explains how the team is applying the system to human trophoblast stem cells, which give rise to specialized placental cells involved in nutrient transport, hormone production, blood vessel remodeling, and immune regulation. Lo describes how AI can distinguish cell populations and identify features that may not be apparent to human observers. The researchers ultimately hope to connect imaging features with gene expression, proteins, and metabolism, allowing cell characteristics and behavior to be predicted from images alone. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41637]

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Author: Language: en-us Episodes: 50

University of California Video Podcasts (Video)
Podcast Episodes
Dementia in Down Syndrome: Is It Inevitable? [not-audio_url] [/not-audio_url]

Duration: 39:31
As part of the 2026 Developmental Disabilities Conference, Dr. Peter Bulova, Professor of General Internal Medicine, The University of Pittsburgh, discusses dementia in people with Down Syndrome. Series: "Developmental D…
The 2000-Year History of Rome and Its Lessons Today [not-audio_url] [/not-audio_url]

Duration: 33:00
Rome survived for 2,000 years. Edward Watts explores the long history of the Roman state and the lessons it offers for the modern world. From its beginnings as a small Italian city-state to its transformation into a Chri…
How Machine Learning Improves Algorithms with Ellen Vitercik [not-audio_url] [/not-audio_url]

Duration: 26:49
Hard optimization problems often look impossible through worst-case analysis, but real-world problems can contain structure that helps algorithms work faster. Ellen Vitercik, Ph.D., of Stanford University explains how ma…
Heart Regeneration in Humans: Are We There Yet? [not-audio_url] [/not-audio_url]

Duration: 58:31
Heart regeneration faces two connected challenges: replacing lost muscle and keeping transplanted cells safe and accepted by the body. Charles Murry, M.D., Ph.D., of USC explains why the adult heart heals major cardiomyo…
Fertility Optimization [not-audio_url] [/not-audio_url]

Duration: 1:21:30
Fertility health affects conception and reproductive planning in important ways. Jennifer Ashby, DAOM, and Maren Shapiro, MD, explain how East Asian medicine principles and daily habits shape fertility optimization. Ashb…
How to Not Know with Simone Stolzoff [not-audio_url] [/not-audio_url]

Duration: 56:13
In an age obsessed with expertise, certainty, and endless self-optimization, author and journalist Simone Stolzoff invites audiences to rediscover the power of curiosity, humility, and not having all the answers. His new…