978 - L-Glutamine for Gut Health, Immunity, Brain & Muscle

978 - L-Glutamine for Gut Health, Immunity, Brain & Muscle

Author: Dr. Michael Ruscio, DC August 4, 2025 Duration: 30:56

L-Glutamine stands as one of the most powerful amino acids for optimizing gut health, muscle function, immune and brain health. It's a common solution for leaky gut, but overall can enhance the improvement of other therapies. In this episode, I'll dive into the benefits of l-glutamine, the best food sources, and effective protocols for different conditions. 

 

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📖Gut reset guide: https://drruscio.com/guides/get-gut-reset-guide/

 

💊 L - Glutamine Supplements:

L-Glutamine Powder: https://store.drruscio.com/products/glutamine-powder

Gut Rebuild Nutrients Powder: https://store.drruscio.com/products/gut-rebuild-nutrients-powder-chocolate

 

👇 Watch more videos like this 👇 

➡️This Leaky Gut Diet Fixes the Root Cause of Poor Gut Health:

https://www.youtube.com/watch?v=6wk9GaT2mtw

➡️The 4 MOST Effective Leaky Gut Treatments:

https://www.youtube.com/watch?v=MW1ezm3d0JQ

➡️A Simple & Effective Leaky Gut Repair Protocol:

https://www.youtube.com/watch?v=5en_twP8DcE

➡️The 10 BEST Foods for Leaky Gut:

https://www.youtube.com/watch?v=f5yXO71ZDec

 

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And if you have any questions or topics you would like covered in the future, let me know in the comments!

 

👇Read these next 👇

➡️How To Heal Leaky Gut:

https://drruscio.com/how-to-heal-leaky-gut/

➡️Best Vitamins for Gut Health: How to Support Your Gut Microbiome:

https://drruscio.com/vitamins-for-gut-health/

➡️8 Best Microbiome Supplements for a Happier, Healthier Gut:

https://drruscio.com/best-microbiome-supplements/

➡️ Probiotics and 5 Other Leaky Gut Supplements to Help You Heal:

https://drruscio.com/leaky-gut-supplements/

 

📌Timestamps

00:00 Intro

01:47 Are you getting enough glutamine? 

03:59 Gut benefits

11;53 Immune benefits

15:38 Brain benefits

17:29 Muscle benefits

19:40 Recommended protocol

21:49 Adverse effects

 

Featured Studies 

📉Glutamine in the Complex Interaction between Gut Microbiota and Health: https://pubmed.ncbi.nlm.nih.gov/31652531/

📉Glutamine Supplementation in Human Exercise and Sport Training:

https://jn.nutrition.org/article/S0022-3166(22)09697-3/fulltext

📉Dietary glutamine supplements for postinfectious IBS:

https://pubmed.ncbi.nlm.nih.gov/30108163/

📉Glutamine Supplementation Enhances the Effects of a Low FODMAP Diet in IBS Management:

https://pubmed.ncbi.nlm.nih.gov/34977110/

📉Glutamine supplementation on IBD: https://pubmed.ncbi.nlm.nih.gov/33745622/

📉Glutamine metabolism & optimal immune and CNS function:

https://pubmed.ncbi.nlm.nih.gov/36285520/

📉Therapeutic benefits of glutamine: https://pubmed.ncbi.nlm.nih.gov/28529738/

📉Glutamine on Immune Function & Post-Operative Complications of Patients With Colorectal Cancer:

https://pubmed.ncbi.nlm.nih.gov/34938760/

📉Supplementation of L-glutamine enhanced mucosal immunity & improved hormonal status of combat-sport athletes: https://pubmed.ncbi.nlm.nih.gov/38193521/

📉Glutamine supplementation on athletic performance, body composition, and immune function:

https://www.clinicalnutritionjournal.com/article/S0261-5614%2818%2930173-0/abstract

📉Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans: https://pubmed.ncbi.nlm.nih.gov/32688366/

📉Oral cystine and glutamine on exercise-induced changes in gastrointestinal permeability and damage markers in young men: https://link.springer.com/article/10.1007/s00394-022-02806-1

📉Glutamine supplementation on gut permeability in adults: https://pubmed.ncbi.nlm.nih.gov/39397201/

📉Glutamine and whey protein improve intestinal permeability and morphology in patients with Crohn's disease:

https://pubmed.ncbi.nlm.nih.gov/22038507/

📉Albendazole therapy and enteric parasites in United States-bound refugees:

https://pubmed.ncbi.nlm.nih.gov/22512482/

📉Glutamine metabolism and optimal immune and CNS function:

https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/glutamine-metabolism-and-optimal-immune-and-cns-function/97AFF4279394640023BE5F9D6635A8C3

📉Glutamine supplementation on serum levels of some inflammatory factors, oxidative stress, and appetite in COVID-19 patients: https://pubmed.ncbi.nlm.nih.gov/34709541/

📉DIetary supplements on markers of exercise-associated gut damage and permeability: https://pubmed.ncbi.nlm.nih.gov/35417467/

 

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g 

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.


Trying to make sense of the latest health trends and research can feel overwhelming. Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare cuts through the noise with grounded, evidence-based conversations. Hosted by clinician and researcher Dr. Michael Ruscio, DC, this podcast explores the practical side of functional health, where complex science is translated into actionable steps you can use. Episodes often start with a curious question-why does one diet work for some but not others, or what does the latest study really mean for everyday health-and follow the evidence where it leads. You’ll hear deep dives into gut health, nutrition, and fitness, balanced with a critical eye that isn’t afraid to debunk popular fads when the data doesn’t support them. The tone is conversational yet precise, reflecting Dr. Ruscio’s dual role as a practicing clinician and a dedicated investigator. Each discussion is built to provide clarity, leaving you with a clearer understanding of how your body works and what might help it work better. It’s important to note that this podcast is for educational and informational purposes. While Dr. Ruscio shares his expertise as a doctor of chiropractic, the content does not constitute personal medical or professional advice. Instead, think of it as a reliable source for thoughtful analysis, helping you have more informed conversations about your own health journey.
Author: Language: English Episodes: 100

Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
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