In this episode, Dr. Jockers sits down with neurologist and bestselling author Dr. David Perlmutter to explore microglia, the brain's immune cells, and the role they may play in protecting the brain from cognitive decline. You'll learn what can shift these cells from a supportive state toward one that promotes neuroinflammation.
Discover why your metabolic health and brain health are deeply connected. Dr. Perlmutter explains how blood sugar, insulin resistance, gut health, and chronic inflammation can influence microglial function and why addressing these factors may be important long before memory problems appear.
You'll also hear practical ways to support your brain through exercise, nutrition, sleep, metabolic flexibility, and other daily habits. Dr. Perlmutter shares why protecting your brain isn't just about what happens later in life—and how the choices you make today can help shape your cognitive future.
In This Episode:
00:00 Amyloid Myth Busted
00:15 Show Intro and Guest
04:18 Book Inspiration Microglia
06:02 Symptom Care vs Root Cause
09:51 Microglia M1 vs M2
11:15 Gut Brain Inflammation Link
15:01 Metabolism Mirrors Microglia
17:57 Infections Vaccines and Triggers
19:31 CTE Diabetes and Feedforward
25:20 New Tools and Beta Amyloid Drugs
30:37 Cochrane Verdict Drugs Fail
33:28 Lifestyle Trial Reverses Decline
38:23 Microglia Lifestyle Levers
39:07 Exercise Myokines Brain Boost
42:20 Alzheimers Risk Epigenetics
45:12 Imaging Microglia TSPO
46:24 Fasting Ketones Brain Fuel
49:45 MCT Oil Memory Care
51:16 POINTER Lifestyle Trial
55:57 Fiber Polyphenols Foods
58:34 Supplements DHA Vitamin D
01:02:23 Key Labs Glucose Tau
01:06:19 Prevention Mission Wrap
01:07:43 Final Thanks Outro
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"Exercise isn't just changing your body. It's changing the environment inside your brain."
Tune into Dr. Jockers Functional Nutrition for conversations that bridge the gap between complex science and practical, daily health choices. Hosted by Dr. David Jockers, a Doctor of Natural Medicine and Functional Nutritionist, this podcast delves into the underlying causes of health challenges rather than just treating symptoms. You’ll hear detailed discussions on metabolic flexibility, the intricacies of gut health, and sustainable methods for reducing systemic inflammation. Dr. Jockers draws from his clinical experience and research, which has been featured in media like ABC and The Dr. Oz Show, to break down strategies for improving brain function, supporting the immune system, and achieving natural detoxification. Each episode is built on a foundation of evidence, yet presented in a way that feels accessible, whether you're deeply invested in fitness or simply seeking a more vibrant life. The focus here is on providing actionable knowledge-the kind that empowers you to make informed decisions about nutrition and lifestyle. This isn't about quick fixes; it's about understanding how your body works and learning the principles that can help it thrive for the long term.
Author: Dr. Jockers
Language: English
Episodes: 50
In this episode, Dr. Jockers sits down with Dr. Paul Savage to review his latest toxin test results and uncover why some markers improved while others remained elevated. You'll learn what these findings reveal about hidd…
In this episode, Dr. David Jockers breaks down the secret truth about nitric oxide and why it's essential for blood pressure, libido, and memory. You'll learn how this molecule boosts circulation, supports organ health,…
In this episode, Dr. David Jockers reveals a powerful olive oil fasting trick that can help activate autophagy, the body's natural cellular cleanup system. You'll learn how high-polyphenol olive oil can support fat burni…
In this episode, Dr. Jockers breaks down the five nutrient deficiencies most closely linked to memory loss, brain fog, and Alzheimer's disease. You'll learn why these deficiencies are more common than most people realize…
In this episode, Dr. Jockers dives into the #1 thing silently destroying your arteries and increasing your risk of heart attacks. You'll learn how high blood sugar and insulin resistance trigger inflammation, plaque buil…
In this episode, Dr. Jockers breaks down simple strategies that can help stabilize blood sugar, reduce cravings, and support the loss of dangerous belly and liver fat. You'll learn why protein is the foundation of metabo…
In this episode, Dr. Jockers sits down with Dr. Josh Axe to explore advanced cellular healing strategies for thyroid, hormones, and metabolism. You'll learn why most thyroid issues aren't caused by the thyroid itself and…
In this episode, Dr. Jockers shares his proven 7-day protocol to heal fatty liver and burn visceral fat naturally. You'll learn how targeted nutrition, fasting, and key supplements can help your liver regenerate and rest…
In this episode, Dr. Jockers dives into the top 10 foods everyone over 40 should eat to burn fat, boost energy, and support hormone balance. He breaks down the science behind how these foods impact your metabolism, libid…
